气相色谱-质谱联用技术研究非洲藜油的生物活性成分

Alagbe John Olujimi Olujimi
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引用次数: 3

摘要

植物化学物质(生物活性化合物)通常被认为是植物来源的化学物质,用于植物生长,防御竞争对手和病原体。它们还具有广泛的药理活性,包括抗心律失常、抗氧化、抗疟疾、血管扩张、抗菌、镇痛、保肝、抗炎、降胆固醇、抗雄激素、抗病毒、抗真菌和免疫调节。采用气相色谱-质谱联用技术对非洲豆科植物Prosopis africana油的生物活性成分进行了研究。通过峰面积分析,共鉴定出73种活性化合物,占77.16%。在油样中鉴定出的主要化合物有;prosogerin A(29.90%)、石竹烯(12.33%)、2,4 -双(1-苯乙基)酚(5.80%)、没食子酸(5.22%)、β-环癸醛(3.11%)、β-谷甾醇(2.50%)、α-萜烯(2.09%)和鞣花酸(2.04%)。其他化合物少于1%,然而,他们发挥不同的药理学性质。结果表明,非洲藜油含有丰富的植物化学物质,具有多种促进健康的特性,可用于治疗人类和动物的多种疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bioactive Compounds of Prosopis Africana Oil (African Mesquite) Using Gas Chromatography and Mass Spectrometry (Gc-Ms) Technique
Phytochemicals (bioactive compounds) are generally regarded as chemicals of plant origin used for plants for growth, defense against competitors and pathogens. They also have a wide range of pharmacological activities including – antiarrhythmic, antioxidant, antimalarial, vasodilatory, antimicrobial, analgesics, hepato-protective, anti-inflammatory, hypo-cholesterolemic, anti-androgenic, antiviral, antifungal and immune-modulatory. This study was carried out to investigate the bioactive compounds of Prosopis africana oil (African mesquite) using gas chromatography – mass spectrometry technique. A total of 73 bioactive compounds (77.16 %) were identified based on their peak areas. The major compounds identified in the oil sample were; prosogerin A (29.90 %), caryophyllene (12.33 %), 2, 4-bis (1-phenylethyl) phenol (5.80 %), gallic acid (5.22 %), β-cyclocitral (3.11 %), β-sitosterol (2.50 %), α-terpinene (2.09 %) and ellagic acid (2.04 %). The other compounds were less than 1 %, however, they exert various pharmacological properties. It was concluded that Prosopis africana oil is loaded with phytochemicals and also has several health promoting properties and it can also be used as a remedy for the treatment of several ailments in human being and animals.
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