基于患者血液管理的贫血围手术期管理

J. Koh
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摘要

围手术期贫血在手术中很常见,是红细胞输注、发病率和死亡率的重要危险因素。长期以来,输血一直是一种常见的做法,也是传统上接受的围手术期贫血的解决方案。然而,越来越多的证据表明,这种传统的治疗方法实际上可能弊大于利。研究表明,输血与发病率和死亡率独立相关。目前,以患者为导向的血液管理和患者血液管理(PBM)正在发生范式转变。PBM包括3个支柱:优化红细胞质量,减少失血量和出血,优化患者对贫血的生理耐受性。在这三种填充物中,围手术期管理主要包括在第二支柱中,但将这三种支柱和策略整合到围手术期途径中应能改善护理过程和患者预后。手术中出血和止血的努力仍在继续,出血的治疗和许多止血方法已经开发出来。近几十年来,微创手术技术使出血减少,其中止血剂、手术器械和新技术在PBM围手术期领域发挥了重要作用。本文总结了为什么需要PBM,以及手术中简单易行的策略。本文主要探讨外科医生在PBM中的作用。主要的PBM方案没有讨论,而是着重于选择性临床实践。(韩国
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perioperative Management of Anemia Based on Patient Blood Management
Perioperative anemia is common during surgery and is an important risk factor for the transfusion of RBC, morbidity and mortality. Blood transfusion has been a common practice for a long time, and has been a traditionally accepted solution to perioperative anemia. However, increasing evidence is now showing that this traditional treatment may actually do more harm than good. Research has shown that transfusion is independently associated with morbidity and mortality. A paradigm shift is currently taking place towards patient-oriented blood management and patient blood management, PBM. PBM consists of 3 pillars: the optimization of the red blood cell mass, reduction of blood loss and bleeding, and optimization of the patients’ physiological tolerance toward anemia. Of the three fillers, perioperative management is mainly included in the second pillar, but integration of these 3 pillars and strategies into perioperative pathways should improve care processes and patient outcome. Bleeding during surgery and efforts to stop it continue, and treatment for bleeding and many hemostatic methods have been developed. In recent decades, minimally invasive surgical techniques have led to a reduction of bleeding, where hemostatic agents, surgical instruments and new techniques have played an important role in the perioperative field of PBM. This paper summarized why PBM is needed, and the strategy during surgery simply and easily. This paper focuses on the surgeons’ role in PBM. The main PBM protocol is not discussed, but rather the paper focuses on selective clinical practice. (Korean
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