一种基于FCN的扩展型细胞检测计数方法

Runkai Zhu, D. Sui, Hong Qin, A. Hao
{"title":"一种基于FCN的扩展型细胞检测计数方法","authors":"Runkai Zhu, D. Sui, Hong Qin, A. Hao","doi":"10.1109/BIBE.2017.00-79","DOIUrl":null,"url":null,"abstract":"Cell detection and counting are critical and essential tasks for many biological and clinical studies. Traditionally, these tasks are usually performed by visual inspection, which is time consuming and prone to induce subjective bias. These make automatic cell counting and detection essential for large- scale and objective studies. Unfortunately, the hard examples such as cell blur, clutter, bleed-through and imaging noise make these tasks extremely challenging. Over the last few years, automatic cell detection and counting have evolved from earlier methods that are often based on filters to the current state-of- the-art deep learning methods. In this paper, we propose a novel efficient method for robust counting and detection task based on fully convolution networks (FCN). Our method is able to handle most of detection and counting problems from different kinds of cell datasets, and can cover most senior microscopy images, such as bright field, pathology stained material and electron. Extensive experiments on the public and private datasets demonstrate the effectiveness and reliability of our approach.","PeriodicalId":262603,"journal":{"name":"2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE)","volume":"62 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"19","resultStr":"{\"title\":\"An Extended Type Cell Detection and Counting Method based on FCN\",\"authors\":\"Runkai Zhu, D. Sui, Hong Qin, A. Hao\",\"doi\":\"10.1109/BIBE.2017.00-79\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cell detection and counting are critical and essential tasks for many biological and clinical studies. Traditionally, these tasks are usually performed by visual inspection, which is time consuming and prone to induce subjective bias. These make automatic cell counting and detection essential for large- scale and objective studies. Unfortunately, the hard examples such as cell blur, clutter, bleed-through and imaging noise make these tasks extremely challenging. Over the last few years, automatic cell detection and counting have evolved from earlier methods that are often based on filters to the current state-of- the-art deep learning methods. In this paper, we propose a novel efficient method for robust counting and detection task based on fully convolution networks (FCN). Our method is able to handle most of detection and counting problems from different kinds of cell datasets, and can cover most senior microscopy images, such as bright field, pathology stained material and electron. Extensive experiments on the public and private datasets demonstrate the effectiveness and reliability of our approach.\",\"PeriodicalId\":262603,\"journal\":{\"name\":\"2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE)\",\"volume\":\"62 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"19\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/BIBE.2017.00-79\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BIBE.2017.00-79","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 19

摘要

细胞检测和计数是许多生物学和临床研究的关键和必不可少的任务。传统上,这些任务通常是通过目测来完成的,这既耗时又容易引起主观偏见。这使得自动细胞计数和检测对于大规模和客观的研究至关重要。不幸的是,诸如细胞模糊、杂乱、穿透和成像噪声等困难的例子使这些任务极具挑战性。在过去的几年里,自动细胞检测和计数已经从早期通常基于过滤器的方法发展到当前最先进的深度学习方法。本文提出了一种基于全卷积网络(FCN)的鲁棒计数和检测方法。我们的方法能够处理来自不同类型细胞数据集的大多数检测和计数问题,并且可以覆盖大多数高级显微镜图像,如亮场,病理染色材料和电子。在公共和私有数据集上进行的大量实验证明了我们方法的有效性和可靠性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An Extended Type Cell Detection and Counting Method based on FCN
Cell detection and counting are critical and essential tasks for many biological and clinical studies. Traditionally, these tasks are usually performed by visual inspection, which is time consuming and prone to induce subjective bias. These make automatic cell counting and detection essential for large- scale and objective studies. Unfortunately, the hard examples such as cell blur, clutter, bleed-through and imaging noise make these tasks extremely challenging. Over the last few years, automatic cell detection and counting have evolved from earlier methods that are often based on filters to the current state-of- the-art deep learning methods. In this paper, we propose a novel efficient method for robust counting and detection task based on fully convolution networks (FCN). Our method is able to handle most of detection and counting problems from different kinds of cell datasets, and can cover most senior microscopy images, such as bright field, pathology stained material and electron. Extensive experiments on the public and private datasets demonstrate the effectiveness and reliability of our approach.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信