M P Maresi, L Baldi, L Balatresi, G Bogi, T Civello, A Cosimi, R De Santis, M Guarnotta, F Baisi, A Parente
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A non-hormonal therapeutic alternative in cervico-vaginal dystrophies.
The pharmaco therapeutic effect of polydeoxyribonucleotide vaginal suppositories in two dosages (PDRN 1,65 mg and PDRN 5 mg)* on vaginal dystrophy was studied. 40 women, aged more than forty, in surgical or physiological climacteric with cervico-vaginal dystrophy were examined. The study was carried out according to the double-blind method, randomized, between groups. Both treatments produced important ameliorations of subjective symptomatology and objective signs. No significant difference emerged between the two preparations. PDRN was proved to be a valid alternative to local hormonal therapies.
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