[皮质类固醇的副作用]。

Medicina (Florence, Italy) Pub Date : 1990-10-01
L Patoia, E Baratta, G Bucaneve, A Rossi, A Perelli, M S Dionisi
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引用次数: 0

摘要

由于皮质类固醇具有抗炎和免疫抑制的特性,以及它们对造血系统和磷酸钙转化的作用,皮质类固醇被广泛用于治疗许多疾病。然而,这些化合物的治疗用途经常与不需要的(主要是A型)效应相关,这些效应直接依赖于其广泛的药理活性。在这项研究中,这些副作用是严格审查和分类的基础上的器官和系统的参与。在可能的情况下,报告发生率、发病机制、类固醇的类型、剂量和时间表,并给出应证明有助于减少副作用发生率和严重性的预防措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Adverse effects of corticosteroids].

Due to their anti-inflammatory and immunosuppressive properties, as well as their action on the hematopoietic system and the calcium phosphate turnover, corticosteroids are widely employed in the treatment of many diseases. However, the therapeutic use of these compounds is frequently associated with unwanted, mainly type A, effects that are directly dependent on the wide spectrum of their pharmacological activities. In this study these side effects are critically reviewed and classified on the basis of the organs and systems involved. Where possible, the incidence, pathogenesis, type of steroid, dose and schedule are reported, and the precautions that should prove useful in reducing the incidence and gravity of the side effects are given.

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