{"title":"免疫制剂大规模冷冻干燥的风险。","authors":"E Sisáková, R Polácek","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Types of biohazards occurring in processing vaccines with freeze-drying method are scrutinized. The attention is payed to risky transfer of infections from animals to human subjects as well as the onset of allergies and contaminations with alien substances, and as a result of impurity of preparation produced. Risks related to the use of freeze-drying are scrutinized in detail.</p>","PeriodicalId":21432,"journal":{"name":"Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove","volume":"33 2","pages":"95-101"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Risks involved in large-scale freeze-drying of immunological preparations.\",\"authors\":\"E Sisáková, R Polácek\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Types of biohazards occurring in processing vaccines with freeze-drying method are scrutinized. The attention is payed to risky transfer of infections from animals to human subjects as well as the onset of allergies and contaminations with alien substances, and as a result of impurity of preparation produced. Risks related to the use of freeze-drying are scrutinized in detail.</p>\",\"PeriodicalId\":21432,\"journal\":{\"name\":\"Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove\",\"volume\":\"33 2\",\"pages\":\"95-101\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Risks involved in large-scale freeze-drying of immunological preparations.
Types of biohazards occurring in processing vaccines with freeze-drying method are scrutinized. The attention is payed to risky transfer of infections from animals to human subjects as well as the onset of allergies and contaminations with alien substances, and as a result of impurity of preparation produced. Risks related to the use of freeze-drying are scrutinized in detail.