基于估计的模型预测控制I型糖尿病患者的血糖:一项模拟研究

Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201) Pub Date : 2001-03-31 DOI:10.1109/NEBC.2001.924729

S. M. Lynch, B. Bequette

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引用次数: 53

摘要

基于人体葡萄糖-胰岛素相互作用的3状态模型，设计了一种约束状态空间模型预测控制器，并在1型糖尿病患者的19状态仿真模型上实现。当受到50 g膳食干扰时，控制器将患者植物的血糖水平维持在60至130 mg/dl之间，显著降低了低血糖/高血糖的风险。

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Estimation-based model predictive control of blood glucose in type I diabetics: a simulation study

A constrained state space model predictive controller, designed based on a 3-state model of the human glucose-insulin interaction, was implemented on a 19-state simulation model of a Type I Diabetic patient. The controller maintained the blood sugar level of the patient plant between the values of 60 and 130 mg/dl, when subjected to a meal disturbance of 50 g, significantly lowering the risk of hypoglycemia/hyperglycemia.

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Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)

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