Successful use of tranexamic acid in the management of child having hereditary angioedema – a case report

Hereditary angioedema (HAE) is a rare disease characterized by recurrent non-pitting subcutaneous edema, involving skin and mucosa of the upper respiratory tract and intestine. Approximately half of the cases manifest clinically in childhood. Due to the rarity of the condition, general practitioners may not be aware of this condition and hence every angioedema attack is managed with systemic steroids. Confirmation of the diagnosis and counseling of the family is also required for education of caregivers and emergency assistance for avoidance of triggering factors (trauma, mental stress, and infection) and prompt control of edematous attacks. We present a case of an 11-year-old child having HAE with recurrent episodes of swelling of face with family history positive and low level of C1 esterase inhibitor, C4 which was managed with systemic use of tranexamic acid.