驻极体对烫伤大鼠红细胞表面电荷的影响

J. Jiang, L. Cui, Z. Xia, X.P. Wang, C. Song
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引用次数: 1

摘要

采用细胞电泳法和唾液酸微量化学量热法测定大鼠红细胞的电泳迁移率(EPM)和唾液酸含量,探讨驻极体对烫伤大鼠红细胞表面电荷的影响机制。结果表明:(1)大鼠烫伤后各时期红细胞EPM和SA含量均较对照组显著降低。(2)负驻极体组EPM和SA含量随时间的延长而显著升高。(3)大鼠烫伤后,驻极体阳性对红细胞EPM和SA含量无显著影响。负驻极体通过稳定红细胞SA含量,修复烫伤大鼠红细胞驻极体状态,改善烫伤大鼠微循环和血液流变学指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of electret on surface charge of red blood cell in scalded rats
The electrophoretic mobility (EPM) and contents of sialic acid (SA) on the red blood cell (RBC) were determined by means of cell electrophoresis and SA micro-chemical calorimetry to explore the mechanism of effect electret on surface charge of RBC in scalded rats. The results indicated that (1) EPM and SA contents of RBC in each period after rat scalded were decreased significantly as compared with those of in control group. (2) In negative electret group, EPM and SA contents were increased markedly with time. (3) Positive electret showed no notable effect on EPM and SA contents of RBC after rats were scalded. Negative electret can improve the microcirculation and hematological rheology index of scalded rats by stabilizing the SA contents of RBC to repair the electret state of RBC in scalded rats.
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