磁致动MOEMS共振生物传感器阵列

E. Timurdogan, Sezin Nargul, H. Kavakli, E. Alaca, H. Urey
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引用次数: 1

摘要

利用生物传感器平台在液体中检测His蛋白。利用自激振荡原理驱动t型镍薄膜悬臂梁,并在悬臂梁上嵌入具有干涉灵敏度的衍射光栅进行传感。实验在定制的1ml液体腔中进行,并证明了5.7ng/ml的检测灵敏度。该方法无标签,鲁棒性强,并允许多路复用。它也不需要任何电子连接到MEMS传感器芯片。因此,它适用于使用便携式设备中的一次性芯片进行实时多分析物筛选。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Magnetic actuated MOEMS resonant biosensor array
A biosensor platform is utilized in liquid for detection of His protein. T-shaped thin film nickel cantilevers are actuated magnetically using self-oscillation principle and the sensing is based on embedded diffraction gratings on the cantilevers with interferometric sensitivity. Experiments are performed in a custom 1ml liquid chamber and 5.7ng/ml detection sensitivity is demonstrated. Method is label-free, robust and allows multiplexing. It also doesn't require any electrical connections to the MEMS sensor chip. Therefore, it is suitable for real-time multi analyte screening using a disposable chip in a portable device.
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