心房颤动二尖瓣手术患者射频与冷冻消融的比较

Sedat Paslı
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摘要

通讯作者:Emin Can Ata, MD. Medipol Mega Üniversite Hastanesi Kalp ve Damar Cerrahisi Bölümü, 34214 Bağcılar, İstanbul,土耳其。摘要:目的:本研究旨在比较两种不同能量源(射频与冷冻消融)治疗心房颤动患者的成功率。患者与方法:2012年8月至2017年8月,共55例患者,其中男性27例,女性28例;平均年龄51.6±11.2岁;范围:44 - 71岁)心房颤动患者在我们诊所的二尖瓣手术中接受了孤立性左房消融。41例采用射频治疗,14例采用冷冻消融治疗。在这两种手术中,消融都是为了隔离所有的肺静脉。射频消融利用射频电流以逐点模式施加,加热组织并导致细胞坏死。低温消融通过将制冷剂(氧化亚氮)以单步模式泵入球囊,从而冷冻组织,从而诱导坏死。通过对照超声心动图和心电图评估两种技术的成功。结果:两种方法在恢复窦性心律方面的成功率无统计学差异。射频消融术组2例患者出现三度房室传导阻滞,需要植入永久性起搏器。相比之下,冷冻消融组没有患者出现相同的阻滞。在接受射频消融术的患者中,术后对肌力支持的需求随着在重症监护室停留时间的延长而增加。结论:我们的研究结果表明,两种技术在房颤二尖瓣手术患者中的成功率相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of radiofrequency and cryoablation procedures for mitral valve surgery patients with atrial fibrillation
Corresponding author: Emin Can Ata, MD. Medipol Mega Üniversite Hastanesi Kalp ve Damar Cerrahisi Bölümü, 34214 Bağcılar, İstanbul, Turkey. Tel: +90 212 460 77 77 e-mail: dr.enata@yahoo.com ABSTRACT Objectives: This study aims to compare the success of two different energy sources, radiofrequency versus cryoablation, in patients with atrial fibrillation. Patients and methods: Between August 2012 and August 2017, a total of 55 patients (27 males, 28 females; mean age 51.6±11.2 years; range, 44 to 71 years) with atrial fibrillation who underwent isolated left atrial ablation during mitral valve surgery in our clinic were included. Radiofrequency was applied to 41 patients and cryoablation to 14 patients. In both procedure, ablation was performed to isolate all pulmonary veins. Radiofrequency ablation utilized a RF current that was applied in a point-by-point mode, heating the tissue and leading to cellular necrosis. Cryogenic ablation induced necrosis by pumping refrigerant (nitrous oxide) through a balloon in a single-step mode, thereby freezing the tissue. The success of both techniques was evaluated through control echocardiography and electrocardiography. Results: There was no statistically significant difference in the success rates of both techniques in terms of returning to the sinus rhythm. Two patients in the radiofrequency ablation group developed third-degree atrioventricular block with the need of permanent pacemaker implantation. In contrast no patient in the cryoablation group developed the same block. In patients who underwent radiofrequency ablation, the need for inotropic support in the postoperative period was higher with prolonged length of stay in the intensive care unit. Conclusion: Our study results show that the success rate of both techniques is similar in patients with atrial fibrillation undergoing mitral valve surgery.
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