Polyuria-polydipsia syndrome approach: clinical case and review

Polyuria-polydipsia syndrome (PPS) compared three-pathologies: nephrogenic or central diabetes insipidus and primary polydipsia. The initial approach considers different causes, and it requires a complete evaluation of the fluid-status support by physician. The diagnosis must exclude frequent abnormalities. Clinical case: A 57-year-old male during his hospitalization documents polydipsia and polyuria with urine volume of 3.5 to 8.45 L/day. We did a test for identify to etiology and other causes was eliminated, concluding a primary polydipsia in a patient with the most important risk was his psychiatric component. An algorithm is proposed according to this experience obtained with the case presented with a review of the topic from the point of view of the internist physician in a patient with a PPS in a controlled-environment.