冠状病毒感染史和SARS-CoV-2感染流行病学

Ricardo Iván Velázquez-Silva
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引用次数: 3

摘要

人类冠状病毒(CoV)的第一个描述是在1965年由泰瑞尔提出的,因其表面的冠状突起而得名。冠状病毒通常会引起人类呼吸道和胃肠道疾病。第一次流行是2002年由SARS-CoV(严重急性呼吸综合征冠状病毒)和2012年由MERS-CoV(中东呼吸综合征冠状病毒)引起的。目前的疫情是由引起COVID-19疾病的新型冠状病毒SARS-CoV-2引起的。第一例病例于2019年12月在中国武汉报告,此后该疾病已在全球传播。世界卫生组织于2020年3月11日宣布其为大流行。截至5月27日,全球共报告确诊病例5488825例,受影响最严重的大陆是美洲,确诊病例2495924例,其次是欧洲,确诊病例2061828例。在墨西哥,第一例病例于2020年2月28日被确诊。据报道,最初在中国,14%的患者表现为中度症状,4.7%的患者表现为危重症,2.3%的患者死亡率在不同国家存在差异。墨西哥的死亡率更高(9.2%)。慢性肾病患者的疾病表现不典型(三分之一的患者腹泻),死亡率较高(16.2-52%)。在肾移植受者中,COVID-19疾病出现更大的并发症和更高的死亡率(10-66%)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Historia de las infecciones por coronavirus y epidemiología de la infección por SARS-CoV-2
The first description of the human coronavirus (CoV) was in 1965 by Tyrrell and was so named because of crown-like projections from its surface. CoV’s usually cause respiratory and gastrointestinal diseases in humans. The first epidemics were caused by SARS-CoV (Severe Acute Respiratory Syndrome CoV) in 2002 and by MERS-CoV (Middle East Respiratory Syndrome CoV) in 2012. The current epidemic is caused by the new coronavirus called SARS-CoV-2 causing of COVID-19 disease. The first cases were reported in Wuhan, China, in December 2019 and since then the spread of the disease has been global. The World Health Organization declared it a pandemic on March 11, 2020. By May 27, a total of 5,488,825 confirmed cases of SARS-CoV-2 have been reported worldwide, the most affected continent is the American with 2,495,924 cases, followed by Europe with 2,061,828 cases. In Mexico, the first case was diagnosed on February 28, 2020. Initially in China it was reported that 14% of patients presented with moderate symptoms, 4.7% critically ill patients, and 2.3% mortality with variability in different countries. In Mexico mortality is higher (9.2%). The presentation of the disease in patients with chronic kidney disease is atypical (diarrhea in one third of patients) and with higher mortality (16.2-52%). In kidney transplant recipients, COVID-19 disease presents with greater complications and higher mortality (10-66%).
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