Rômulo Bagano Menezes, R. Sampaio, A. Guimarães, L. Olivieri, M. L. Lima, A. Ladeia
{"title":"微白蛋白尿与肥胖和超重妇女的内皮功能障碍无关,但与空腹血糖密切相关","authors":"Rômulo Bagano Menezes, R. Sampaio, A. Guimarães, L. Olivieri, M. L. Lima, A. Ladeia","doi":"10.17267/2317-3386bjmhh.v1i2.239","DOIUrl":null,"url":null,"abstract":"This study aimed to evaluate the association between endothelial dysfunction and microalbuminuria levels in overweight and obese women. Methods: This cross-sectional study analyzed secondary data of patients with BMI ≥ 25 Kg/m 2 who had microalbuminuria and endothelial function test already performed and inserted into the survey database. The endothelial function was evaluated by reactive hyperemia test (endothelium-dependent vasodilation). Results: This study included 41 women aged of 53 ± 11 years, BMI of 32.56 ± 5.06 Kg/m 2 , WC of 100.36 ± 23.21 cm. There was no correlation between microalbuminuria and endothelial function. A multivariate logistic regression analysis identified glucose fasting (β = 0.804; p < 0,00,1) and HDL (β = - 0.309; p = 0.048) levels as independent predictors of microalbuminuria. Conclusion: Microalbuminuria is not useful as a marker of subclinical atherosclerosis in this population, however can be associated to glucose fasting and HDL levels.","PeriodicalId":280405,"journal":{"name":"Brazilian Journal of Medicine and Human Health","volume":"198 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2013-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MICROALBUMINURIA IS NOT ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN OBESE AND OVERWEIGHT WOMEN, BUT IS STRONGLY CORRELATED WITH FASTING GLYCEMIA\",\"authors\":\"Rômulo Bagano Menezes, R. Sampaio, A. Guimarães, L. Olivieri, M. L. Lima, A. Ladeia\",\"doi\":\"10.17267/2317-3386bjmhh.v1i2.239\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study aimed to evaluate the association between endothelial dysfunction and microalbuminuria levels in overweight and obese women. Methods: This cross-sectional study analyzed secondary data of patients with BMI ≥ 25 Kg/m 2 who had microalbuminuria and endothelial function test already performed and inserted into the survey database. The endothelial function was evaluated by reactive hyperemia test (endothelium-dependent vasodilation). Results: This study included 41 women aged of 53 ± 11 years, BMI of 32.56 ± 5.06 Kg/m 2 , WC of 100.36 ± 23.21 cm. There was no correlation between microalbuminuria and endothelial function. A multivariate logistic regression analysis identified glucose fasting (β = 0.804; p < 0,00,1) and HDL (β = - 0.309; p = 0.048) levels as independent predictors of microalbuminuria. Conclusion: Microalbuminuria is not useful as a marker of subclinical atherosclerosis in this population, however can be associated to glucose fasting and HDL levels.\",\"PeriodicalId\":280405,\"journal\":{\"name\":\"Brazilian Journal of Medicine and Human Health\",\"volume\":\"198 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-09-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brazilian Journal of Medicine and Human Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17267/2317-3386bjmhh.v1i2.239\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Journal of Medicine and Human Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17267/2317-3386bjmhh.v1i2.239","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
MICROALBUMINURIA IS NOT ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN OBESE AND OVERWEIGHT WOMEN, BUT IS STRONGLY CORRELATED WITH FASTING GLYCEMIA
This study aimed to evaluate the association between endothelial dysfunction and microalbuminuria levels in overweight and obese women. Methods: This cross-sectional study analyzed secondary data of patients with BMI ≥ 25 Kg/m 2 who had microalbuminuria and endothelial function test already performed and inserted into the survey database. The endothelial function was evaluated by reactive hyperemia test (endothelium-dependent vasodilation). Results: This study included 41 women aged of 53 ± 11 years, BMI of 32.56 ± 5.06 Kg/m 2 , WC of 100.36 ± 23.21 cm. There was no correlation between microalbuminuria and endothelial function. A multivariate logistic regression analysis identified glucose fasting (β = 0.804; p < 0,00,1) and HDL (β = - 0.309; p = 0.048) levels as independent predictors of microalbuminuria. Conclusion: Microalbuminuria is not useful as a marker of subclinical atherosclerosis in this population, however can be associated to glucose fasting and HDL levels.