Chaudhry Iftikhar Ahmed, Khan Mohammad Nasim, Alqahtani Yousif A, Alghamdi Abdullah, AlFraih Othman M, AlAbdulhai Meenal A, Chaudhry Ikram Ul-Haq
{"title":"肺先天性囊性腺瘤样畸形:一种罕见的成人先天性畸形并文献复习","authors":"Chaudhry Iftikhar Ahmed, Khan Mohammad Nasim, Alqahtani Yousif A, Alghamdi Abdullah, AlFraih Othman M, AlAbdulhai Meenal A, Chaudhry Ikram Ul-Haq","doi":"10.29328/journal.jprr.1001038","DOIUrl":null,"url":null,"abstract":"Congenital cystic adenomatoid malformation of the lung (CCAM) is characterized by an adenomatoid proliferation of bronchiole-like structures and cysts formation. The condition is most commonly found in newborns and children and may be associated with other malformations; rarely, the presentation is delayed until adulthood. We herein report two cases of CCAM in adult patients. 22 years old healthy female with pre-employment health screening chest X-ray showed a lesion in the upper lobe of the right lung. In another case, a computed tomographic scan of the thorax (CT) confirmed a mass in the upper right lung. A 28-year-old male presented with recurrent respiratory tract infection resistant to antimicrobial therapy. CT scan of the thorax showed a mass in the left lung upper zone. Surgical resection was performed in both cases, and histopathology of the resected specimen showed both cases were consistent with the CCAM.","PeriodicalId":398097,"journal":{"name":"Journal of Pulmonology and Respiratory Research","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pulmonary congenital cystic adenomatoid malformation: a rare congenital abnormality in adults and review of literature\",\"authors\":\"Chaudhry Iftikhar Ahmed, Khan Mohammad Nasim, Alqahtani Yousif A, Alghamdi Abdullah, AlFraih Othman M, AlAbdulhai Meenal A, Chaudhry Ikram Ul-Haq\",\"doi\":\"10.29328/journal.jprr.1001038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Congenital cystic adenomatoid malformation of the lung (CCAM) is characterized by an adenomatoid proliferation of bronchiole-like structures and cysts formation. The condition is most commonly found in newborns and children and may be associated with other malformations; rarely, the presentation is delayed until adulthood. We herein report two cases of CCAM in adult patients. 22 years old healthy female with pre-employment health screening chest X-ray showed a lesion in the upper lobe of the right lung. In another case, a computed tomographic scan of the thorax (CT) confirmed a mass in the upper right lung. A 28-year-old male presented with recurrent respiratory tract infection resistant to antimicrobial therapy. CT scan of the thorax showed a mass in the left lung upper zone. Surgical resection was performed in both cases, and histopathology of the resected specimen showed both cases were consistent with the CCAM.\",\"PeriodicalId\":398097,\"journal\":{\"name\":\"Journal of Pulmonology and Respiratory Research\",\"volume\":\"46 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pulmonology and Respiratory Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29328/journal.jprr.1001038\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pulmonology and Respiratory Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29328/journal.jprr.1001038","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Pulmonary congenital cystic adenomatoid malformation: a rare congenital abnormality in adults and review of literature
Congenital cystic adenomatoid malformation of the lung (CCAM) is characterized by an adenomatoid proliferation of bronchiole-like structures and cysts formation. The condition is most commonly found in newborns and children and may be associated with other malformations; rarely, the presentation is delayed until adulthood. We herein report two cases of CCAM in adult patients. 22 years old healthy female with pre-employment health screening chest X-ray showed a lesion in the upper lobe of the right lung. In another case, a computed tomographic scan of the thorax (CT) confirmed a mass in the upper right lung. A 28-year-old male presented with recurrent respiratory tract infection resistant to antimicrobial therapy. CT scan of the thorax showed a mass in the left lung upper zone. Surgical resection was performed in both cases, and histopathology of the resected specimen showed both cases were consistent with the CCAM.