An Indian Evidence-Based Study of Prevalence, Phenotypic Features, Lifestyle Modifications of Polycystic Ovarian Syndrome Patients

Objective: An Indian evidence-based study of Prevalence, phenotypic features, Lifestyle modifications of polycystic ovarian syndrome patients Design: A large-scale population-based study was conducted among women of reproductive age in the state of Telangana between December 2018 and December 2020. Setting: A randomized multi - stage stratified sampling method was adopted. PCOS screening was based on questionnaires. Blood samples for hormonal analysis were collected from those with probable and definitive PCOS cases. Main Outcome Measure: Through our study we found the prevalence of polycystic ovarian syndrome in the Urban and rural areas of Hyderabad ,Telangana (South India) to be 6.5- 6.8% Results: In total, 688 patients were screened for PCOS,573 patients were enrolled of which 281 were from urban and 292 were from rural respectively. Of which probable PCOS cases 28 were probable PCOS and 17 were known cases and 83 were controls in the urban region.17 were probable PCOS and 10 were known cases and 73 were controls in the rural region. The overall count of probable cases were 45, Known PCOS were 27 and controls were 153.Of which 348 patients were not included due to various reasons were not included. Probable cases were 27.29 + 7.14,Controls cases were 29.67 + 6.88 with ap value 0.001 had PCOS from Urban and Rural Area. The PCOS phenotypes were 8% clinical HA (hirsutism, H), alopecia (7%), Acanthosis (3%) Acne was (6%), USG (35%) in urban and Rural regions.55 % and 45% biochemical assessment done in Urban and Rural area respectively. Hormonal Assay was 75% and 25 % of the women with PCOS resided in Urban and Rural regions respectively. Hyperinsulinemia was observed in probable cases compared to the controls.