基于数值模型的轴流式左室辅助装置在不同工作模式下的性能分析

Yimin Wang, Yunpeng Zhang, Xiangyu Wu
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引用次数: 2

摘要

轴流式左室辅助装置(LVADs)的工作模式对血流灌注的影响尚不清楚。本研究采用心血管系统耦合LVAD的数值模型,对轴流式LVAD的血流动力学进行了研究。该数值模型将人体循环系统细分为若干个集总参数块,并用各种电路元件表示。本文选取了轴流lvad的共脉冲、反脉冲和等速三种工作模式。结果表明,在三种工作模式下,血流沿整个通道畅通无阻。共脉模式适合于有一定心功能的患者,因为这种模式在心脏收缩期保持较高的血液灌注,减轻了心脏舒张期主动脉的压力负荷。相反,反脉冲模式更适合心功能严重受损的患者,因为该模式在整个心脏周期内保持较高的血液灌注。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Performance Analysis of Axial Flow Left Ventricular Assist Devices Under different working modes Based on the Numerical Model
The effect of working modes of axial flow left ventricular assist devices (LVADs) on blood perfusion has not been clearly elucidated. In this study, hemodynamics of axial flow LVAD was investigated by using the numerical model of the cardiovascular system coupled with LVAD. The numerical model subdivides the human circulatory system into several lumped parameter blocks, which are represented by various circuit elements. In this paper, we chosen three working modes of axial flow LVADs, named, the co-pulse, counter pulse and constant speed modes. Results show that the blood fluid flowed smoothly along the whole passage under three working modes. The co-pulse mode was suitable for patients with certain cardiac function because this mode kept high blood perfusion during systole and reduced the pressure load on the aorta the diastole. By contrast, the counter pulse mode was more suitable for patients with severely impaired cardiac function because this mode kept a high blood perfusion during a whole cardiac cycle.
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