外部因素对无创血氧测量准确度的影响

Y. M. Snizhko, V. Sarana
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引用次数: 0

摘要

本文研究了一种基于脉搏血氧测量的移动设备检测方法。该方法在人体透明部位获得与血液脉动相关的生物信号。最广泛接受使用这种方法的领域是医院护理。在这些情况下,脉搏血氧仪是监测急诊患者的最佳解决方案。脉搏血氧测量的一个很有前途的领域是体育锻炼。它只需要简单的夹子,如耳夹,手指夹,发带等。但该方法存在信号弱、噪声比大、运动伪影、低灌注等问题。我们使用MAX30100血氧计和心率传感器集成电路从红光和红外光发射二极管(LED)获取血脉搏波信号。该设备通过将LED和光电探测器放置在人体的薄皮肤上(如指尖、手腕或耳垂)来测量人体血液中的氧饱和度。MAX30100是一个14针表面贴装集成电路,包含用于测量人心率的传感器。它还可以间接测定一个人血液中的氧饱和度。MAX30100为医疗监视器和可穿戴健身设备提供完整的脉搏血氧仪和心率测量解决方案。当每个LED向人的手指发光时,集成的光电探测器会测量由血容量变化引起的光的变化。集成的16位模数转换器(ADC)具有可编程采样率,可将光电探测器输出转换为数字值。MAX30100滤除干扰准确读数的环境光。数据通过串行I2C接口读取到计算机进行进一步处理。LED电流可编程从0到50 mA与适当的电源电压。LED脉冲宽度可以在200µs到1.6 ms之间进行编程,以根据用例优化测量精度和功耗。SpO 2算法对红外LED的波长相对不敏感,但红色LED的波长对正确解释数据至关重要。温度传感器的数据可以用来补偿环境温度变化带来的误差。在实验中,我们记录了不同条件下的氧浓度值。在低肌肉活动下,我们观察到在各种外部条件下测量值的高稳定性和可重复性。然而,在高肌肉活动的情况下,测量到的信号中有各种各样的伪影,导致了效果的扭曲。我们确定了测量有效性的边界,并建议使用自适应滤波器,以便更可靠地从光信号中区分脉冲波。这些设备可以应用于健身训练、医疗监测和可穿戴设备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The influence of external factors on the accuracy of non-invasive measuring of oxygen in blood
In this paper we investigated a pulse oximetry-based method for mobile devices. This method obtains bio-signals related to blood pulsation in transparent parts of body. The most widely accepted field for use of this method is hospital care. In these cases a pulse oximeter is the best solution for the monitoring of emergency patients. A promising field for pulse oximetry is physical exercise. It only requires simple clips such as ear-clips, finger-clips, headbands etc. However this method presents some difficulties: weak signal, noise ratio, motion artefacts, low perfusion. We used a MAX30100 Oximeter and Heart Rate Sensor integrated circuit to obtain signals of blood pulse waves from red and infrared light emission diodes (LED). This device measures the oxygen saturation of a person’s blood by placing an LED and a photodetector against the thin skin of a person’s body, such as a fingertip, wrist or earlobe. The MAX30100 is a 14-pin surface mount integrated circuit that contains sensors for measuring a person’s heart rate. It can also indirectly determine the oxygen saturation of a person’s blood. The MAX30100 provides a complete pulse oximetry and heart rate measurement solution for medical monitors and wearable fitness devices. As each LED emits light into a person’s finger, the integrated photodetector measures variations in light caused by changes in blood volume. An integrated 16-bit analog to digital converter (ADC) with programmable sample rate converts the photodetector output to a digital value. The MAX30100 filters out ambient light that can interfere with an accurate reading. Data are read through a serial I2C interface to computer for further processing. The LED current can be programmed from 0 to 50 mA with proper supply voltage. The LED pulse width can be programmed from 200 µs to 1.6 ms to optimize measurement accuracy and power consumption based on use cases. The SpO 2 algorithm is relatively insensitive to the wavelength of the infrared LED, but the red LED’s wavelength is critical to correct interpretation of the data. The temperature sensor data can be used to compensate errors with ambient temperature changes. During the experiments we registered oxygen concentration values under different conditions. With low muscular activity we observed high stability and repeatability of measuring values under various exterior conditions. However, with high muscular activity there were various artefacts in the gauged signals that led to contortion of effects. We identified the boundaries of the validity of measuring and propose the use of an adapted filter in order to distinguish pulse waves from optical signals more reliably. These devices can be applied in fitness training , medical monitoring and used as wearable devices.
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