支架辅助盘绕未破裂的宽颈或不利圆颈比的类旁动脉瘤:腹侧壁与背侧壁的倾向评分匹配分析结果。

H. Ni, Yunfei Hang, Sheng Liu, Z. Jia, Hai-bin Shi, Lin-Bo Zhao
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摘要

目的探讨基于投影分布的支架辅助线圈栓塞治疗未破裂宽颈类旁动脉瘤的临床安全性和有效性。方法2015年11月至2020年9月,236例患者中267例未破裂的腹旁动脉瘤被确诊为颈宽或不利的穹颈比,并采用支架辅助卷曲技术治疗。该节段动脉瘤的分类简化为背侧组(位于前壁)和腹侧组(非背侧)。通过倾向评分匹配分析,比较两组患者的临床和影像学资料。结果267个动脉瘤中186个位于腹侧壁,81个位于背侧壁。与腹壁动脉瘤相比,背壁动脉瘤体积更大(p < 0.001),颈宽(p = 0.001),圆颈比(p = 0.023)更高。倾向评分匹配分析发现,与腹侧组相比,背侧组在即时(残余囊,39.4%比18.2%,p = .007)和随访血管造影(残余囊,14.8%比1.9%,p = .037)中出现不良结果的可能性明显更高,复发率差异有统计学意义(9.3%比0%,p = .028)。手术相关并发症的发生率没有显著差异,但在临床恶化的背侧组发生了一次血栓栓塞事件。结论位于腹侧壁的类突旁动脉瘤可优先采用传统支架辅助卷绕术。支架辅助下的背壁动脉瘤复发率相对较高,可能需要其他治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stent-assisted coiling of unruptured paraclinoid aneurysms with wide neck or unfavorable dome-to-neck ratio: Results of ventral wall vs dorsal wall with propensity score matching analysis.
OBJECTIVE This study aimed to evaluate the clinical safety and efficacy of stent-assisted coil embolization of unruptured wide-necked paraclinoid aneurysms based on the projection distribution. METHODS Between November 2015 and September 2020, 267 unruptured paraclinod aneurysms in 236 patients were identified with a wide neck or unfavorable dome-to-neck ratio and treated with stent-assisted coiling technique. The classification of this segment aneurysms was simplified to the dorsal group (located on the anterior wall) and ventral group (Non-dorsal). Following propensity score matching analysis, the clinical and radiographic data were compared between the two groups. RESULTS Among 267 aneurysms, 186 were located on the ventral wall and 81 were on the dorsal wall. Dorsal wall aneurysms had a larger size (p < .001), wider neck (p = .001), and higher dome-to-neck ratio (p = .023) compared with ventral wall aneurysms. Propensity score-matched analysis found that dorsal group had a significantly higher likelihood of unfavorable results in immediate (residual sac, 39.4% vs. 18.2%, p = .007) and follow-up angiography (residual sac, 14.8% vs. 1.9%, p = .037) compared with ventral group, with significant difference in recurrence rates (9.3% vs. 0%, p = .028). The rates of procedure-related complications were not significantly different, but one thromboembolic event occurred in the dorsal group with clinical deterioration. CONCLUSIONS Traditional stent-assisted coiling can be given preference in paraclinoid aneurysms located on the ventral wall. The relatively high rate of recurrence in dorsal wall aneurysms with stent assistance may require other treatment options.
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