气相色谱辅助质谱指纹图谱分析薄荷叶根挥发性成分

M. Farman, N. Nasreen, N. Semmar, Saud Ahmad
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引用次数: 0

摘要

Torilis leptophyla通常被称为猪鬃果篱欧芹,因其治疗肝脏和胃肠道疾病的潜力而被广泛认可。直到今天,还没有科学证据支持这一说法。因此,本研究旨在全面全面地了解薄缕草的挥发性成分。联用色谱分析显示,正己烷提取物中有11种挥发性有机化合物,氯仿提取物中有5种。鉴定出的化合物属于不同的类别,包括萜烯、酯类、酚类、碳氢化合物和醇类。在醇类中,镰镰醇被发现是一种新的抗真菌剂,以前没有在鸢尾属中报道过。这些分析/结构化学调查突出了与使用这种植物作为治疗各种传染病的民间药物有关的第一种代谢模式。此外,他们还确认了植物化学物质的代谢库在药物发现和开发中可以发挥重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gas Chromatography aided Mass Spectral Fingerprinting of Volatile Phytoconstituents from Torilis leptophylla Roots
Torilis leptophylla commonly known as bristle fruit hedge parsley is widely acknowledged for its potential to treat liver and gastrointestinal disorders. Till today no scientific evidence has been reported to support this claim. So the present investigation was carried out to get an inclusive picture of volatile phytoconstituents of Torilis leptophylla. Hyphenated chromatographic technique revealed the presence of 11 VOC’s from n-Hexane extract and 5 from chloroform extract. Identified compounds belonged to different classes including terpenes, esters, phenols, hydrocarbons and alcohols. Among alcohols, falcarinol was revealed to be a de-novo antifungal agent not previously reported in the genus Torilis. These analytical/structural chemical investigations highlighted a first metabolic pattern associated with the use of this plant as a folk medicine for the cure of various infectious diseases. Moreover, they ratified that the metabolic pool of phytochemicals can play a noteworthy role in drug discovery and development.
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