Sofiene Tlili, Raoua Ben Brahim, J. Sabatier, I. Regaya
{"title":"海洋刺胞动物和腹足动物的毒素和毒液:针对离子通道的多样性和潜在药物","authors":"Sofiene Tlili, Raoua Ben Brahim, J. Sabatier, I. Regaya","doi":"10.2174/2666121701666211124154216","DOIUrl":null,"url":null,"abstract":"\n\nA diversity of marine invertebrates, such as cnidarians are rich sources of large bio-active molecules. This chemo-diversity of bio-active compounds has a promising potential in several biotechnological and therapeutic applications. On the basis of a comparative bibliographic approach, we intend in this review to present and discuss an overview of: i) the diversity of marine invertebrates as a candidate for bio-active molecules production; ii) the diversity of bio-active compounds and venom derived from these organisms; iii) the relationship between, the diversity of these marine organisms and the structure of the toxins they secrete. In this bibliographic study, a focus is going to be made on protein neurotoxins targeting ion channels. We also discuss the potential link between the bioecological characteristics of cnidarians and the diversity of toxins.\n","PeriodicalId":438678,"journal":{"name":"Venoms and Toxins","volume":"7 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Toxins and venoms from marine cnidarians and gastropods: diversity and potential drugs targeting the ion channels\",\"authors\":\"Sofiene Tlili, Raoua Ben Brahim, J. Sabatier, I. Regaya\",\"doi\":\"10.2174/2666121701666211124154216\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nA diversity of marine invertebrates, such as cnidarians are rich sources of large bio-active molecules. This chemo-diversity of bio-active compounds has a promising potential in several biotechnological and therapeutic applications. On the basis of a comparative bibliographic approach, we intend in this review to present and discuss an overview of: i) the diversity of marine invertebrates as a candidate for bio-active molecules production; ii) the diversity of bio-active compounds and venom derived from these organisms; iii) the relationship between, the diversity of these marine organisms and the structure of the toxins they secrete. In this bibliographic study, a focus is going to be made on protein neurotoxins targeting ion channels. We also discuss the potential link between the bioecological characteristics of cnidarians and the diversity of toxins.\\n\",\"PeriodicalId\":438678,\"journal\":{\"name\":\"Venoms and Toxins\",\"volume\":\"7 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Venoms and Toxins\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/2666121701666211124154216\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Venoms and Toxins","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2666121701666211124154216","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Toxins and venoms from marine cnidarians and gastropods: diversity and potential drugs targeting the ion channels
A diversity of marine invertebrates, such as cnidarians are rich sources of large bio-active molecules. This chemo-diversity of bio-active compounds has a promising potential in several biotechnological and therapeutic applications. On the basis of a comparative bibliographic approach, we intend in this review to present and discuss an overview of: i) the diversity of marine invertebrates as a candidate for bio-active molecules production; ii) the diversity of bio-active compounds and venom derived from these organisms; iii) the relationship between, the diversity of these marine organisms and the structure of the toxins they secrete. In this bibliographic study, a focus is going to be made on protein neurotoxins targeting ion channels. We also discuss the potential link between the bioecological characteristics of cnidarians and the diversity of toxins.