T. Suzuki, Y. Teramura, K. Inokuma, I. Kanno, H. Iwata, H. Kotera
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Development of Biosensor Chip for Clinical Diagnosis Using Surface Plasmon Resonance Imaging with Multi-Microchannels
A compact biosensor chip for clinical diagnosis is presented. The proposed biochip integrated three independent microchannels on one chip partially coated with Au thin film as a surface plasmon resonance (SPR) excitation layer. For clinical diagnosis, the affinity binding of unlabeled biological molecules onto the Au surface can be quantitatively analyzed by SPR imaging with the multi-microchannels, i.e. one biosample and two reference flows to obtain an analytical curve
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