自组装有机纳米管:药物设计和发现的新平台

H. Fenniri
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引用次数: 0

摘要

自组装和自组织过程是连接化学反应的还原论与生命动态系统的复杂性和出现的线索。人工自组装的原理来源于自然及其过程,并利用这种理解来设计具有预定义功能的纳米级器件。然而,复杂形式的有组织物质不能一个键一个键地合成。相反,需要一种基于非共价力的新型合成来自下而上地生成功能实体。化学科学的这一不断发展的领域挑战了传统伍德沃德化学的许多基本前提:物质有组织状态的概念化不仅需要对化学反应性有深入的了解,而且需要对将化学信息转化为功能上层结构所必需的非共价力有深入的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Self-Assembled Organic Nanotubes: A Novel Platform for Drug Design and Discovery
Self-assembly and self-organization processes are the thread that connects the reductionism of chemical reactions to the complexity and emergence of a living dynamic system. Artificial self-assembly derives its principles from nature and its processes, and uses this understanding to design nanoscale devices with predefined function. However, complex forms of organized matter cannot be synthesized bond-by-bond. Rather, a new type of synthesis based on noncovalent forces is necessary to generate functional entities from the bottom up. This growing field of the chemical sciences challenges much of the basic premises of conventional Woodwardian chemistry: The conceptualization of an organized state of matter requires in-depth understanding not only of chemical reactivity but also of noncovalent forces necessary to translate chemical information into functional superstructures.
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