Piotr Roszkowski , Stefan Czarnocki , Jan K. Maurin , Aleksandra Siwicka , Anna Zawadzka , Joanna Szawkało , Andrzej Leniewski , Zbigniew Czarnocki
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Variety of natural products derived from tryptophan and stereoselective synthesis of tetrahydro-β-carboline derivatives of pharmacological importance
The use of chiral inductors belonging to different classes of compounds is elaborated. Tetrahydro-β-carboline derivatives were constructed stereoselectively by the use of (R)-1-arylethylamine and l-amino acids. Asymmetric transfer hydrogenation was proven highly effective in enantioselective synthesis of several alkaloids.
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