精神障碍合并冠状病毒感染临床1例

M. Jumagaliyeva, D. Ayaganov, V. Yuldashev, L. Akhmadeeva
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引用次数: 0

摘要

(COVID-19)。除了全身和呼吸道症状外,SARS-CoV-2还会引起神经系统疾病,因为它是一种嗜神经病毒。许多科学家认为,SARS-CoV-2可以通过血管紧张素转换酶2的功能性受体进入神经系统,这种受体存在于神经胶质细胞、神经元、骨骼肌和其他器官中。神经系统并发症表现为中枢神经系统、周围神经系统和脑神经的损害以及精神障碍。精神疾病是由于大脑感染SARS-CoV-2后的神经炎症和神经元死亡而发展的。本文描述了一例63岁男性新冠病毒感染合并明显精神障碍的临床病例,他以前从未有过任何精神疾病。上述临床实例表明,研究COVID-19与精神疾病之间的因果关系非常重要。从中长期来看,预计COVID-19将在COVID-19恢复期间导致精神健康障碍。此外,预计在感染新冠病毒之前精神健康的精神障碍患者也会增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A clinical case of co-occurring mental disorder and coronavirus infection
(COVID-19). In addition to systemic and respiratory symptoms, SARS-CoV-2 causes neurological disorders, as it is a neurotropic virus. Many scientists assume that SARS-CoV-2 can enter the nervous system through the functional receptor of angiotensin-converting enzyme 2, which is present in glial cells, neurons, skeletal muscles, and other organs. Neurological complications are manifested by damage to the central nervous system, peripheral nervous system, and cranial nerves, as well as by mental disorders. Mental illnesses develop due to neuroinflammation and neuronal death after brain infection with SARS-CoV-2.The article describes a clinical case of a 63-year-old man with the co-occurring novel coronavirus infection and obvious mental disorder who has never had any mental illnesses before. The given clinical example demonstrates the importance of studying the cause-and-effect relationship between COVID-19 and mental illness. In the mediumand long-term perspective, COVID-19 is expected to result in mental health disorders during COVID-19 recovery. Besides, an increase in the number of patients with mental disorders who were mentally healthy before COVID-19 infection is also expected.
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