非适应性组抑制剂试验

A. Ganesan, S. Jaggi, Venkatesh Saligrama
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引用次数: 10

摘要

本文研究了Farach等人引入的抑制剂(GTI)的群体试验。有三种类型的项目,d缺陷,r抑制剂和n-d-r正常项目在n个项目的群体。测试中任何抑制剂的存在都可以阻止缺陷基因的表达。针对该模型,我们提出了一种具有低复杂度解码算法的概率非自适应池化设计。我们表明,使用所提出的算法,在r = O(d)和d = O(r)的范围内,保证错误概率消失的恢复所需的测试次数的样本复杂度分别为T = O(d)和d = O(r)。在前一种情况下,测试的次数满足下界阶,而在后一种情况下,测试的次数被证明超过下界阶一个log r / d乘因子。所提出的译码算法的译码复杂度为0 (nT)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-adaptive group testing with inhibitors
Group testing with inhibitors (GTI) introduced by Farach at al. is studied in this paper. There are three types of items, d defectives, r inhibitors and n-d-r normal items in a population of n items. The presence of any inhibitor in a test can prevent the expression of a defective. For this model, we propose a probabilistic non-adaptive pooling design with a low complexity decoding algorithm. We show that the sample complexity of the number of tests required for guaranteed recovery with vanishing error probability using the proposed algorithm scales as T = O(d log n) and equation in the regimes r = O(d) and d = o(r) respectively. In the former regime, the number of tests meets the lower bound order while in the latter regime, the number of tests is shown to exceed the lower bound order by a log r over d multiplicative factor. The decoding complexity of the proposed decoding algorithm scales as O(nT).
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