基于离散小波变换和分形维数的Nd5蛋白序列相似性分析

Xiaocui Dang, Lina Yang, Yuanyan Tang, Pu Wei, Hailong Su
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引用次数: 0

摘要

在生物信息系统中,生物序列分析是当今生物信息学研究的一个主要问题。提出了一种基于离散小波变换、分形维数和单聚类方法的蛋白质序列相似性分析方法。采用离散小波对含有生物信息的数字信号进行多元分解。利用基于小波分解的Higuchi算法,结合蛋白质的多种性质,研究了蛋白质一级结构的分形特征。通过解析计算得到不同蛋白质之间的距离矩阵。系统发育树,以及蛋白质序列的类似分析。结果表明,与传统方法相比,小波变换、分形维数方法和多属性分析法能更全面、可靠、快速地分析蛋白质序列的相似性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nd5 Protein Sequence Similarity Analysis Based On Discrete Wavelet Transform And Fractal Dimension
In biological information systems, the analysis of biological sequences is a major problem in today’s bioinformatics research. In this paper, a method for protein sequence similarity analysis based on discrete wavelet transform and fractal dimension and single clustering method is proposed. Multivariate decomposition of digital signals containing biological information is performed by discrete wavelets. Using the Higuchi algorithm based on wavelet decomposition, the fractal characteristics of the primary structure of the protein were studied using multiple properties of the protein. The distance matrix between different proteins is obtained by analytical calculation. Phylogenetic tree, and similar analysis of protein sequences. The results show that compared with the traditional methods, wavelet transform and fractal dimension methods and multiple attribute analysis can analyze the similarity of protein sequences more comprehensively, reliably and quickly.
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