学术医学界对基于纳米技术的传染病管理策略的知识水平:一项简短的研究

Garcia Ls
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摘要

纳米技术是一个集化学、工程、生物学和医学于一体的跨学科研究领域。在癌症生物学中已经确定了几种有用的纳米技术应用,包括早期检测肿瘤和癌症生物标志物的技术,以及开发利用传统技术无法实现的治疗方法,正如当前COVID-19大流行期间所证明的那样,纳米技术可以在全球卫生中发挥重要作用。从更好的筛查和诊断到治疗方法和疫苗,以及健康监测设备,纳米技术支持的方法有可能在传染病领域产生切实的影响。在预防和治疗感染方面,有人建议不仅专业人员(如医院临床医生在感染治疗期间)使用材料,而且每个人(如在家中使用的涂料中的纳米粒子或非处方纳米药物)也应使用这些材料。由于这个原因,未来的工作必须依靠工程师、临床医生和环境科学家(以及其他领域的科学家)之间的合作,从化学、杂质和毒性方面全面表征这种纳米材料。随着安全使用指南的建立,纳米材料可以安全地用于抗菌材料设计的重要和发展领域。我们应该为纳米技术在这些协同抗感染努力中的未来感到兴奋(而不是害怕)。尽管纳米技术是一个迅速发展的研究领域,但它的进步在很大程度上仍然是未知的。具体到传染病,探索学术医学界对这一多学科科学对其预防和控制的贡献的知识水平将是有趣的,这是本研究的主要目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Level of Knowledge of the Academic Medical Community about Nanotechnology-Based Strategies Developed to Manage Infectious Diseases: A Short Study
Nanotechnology is an interdisciplinary research field that integrates chemistry, engineering, biology, and medicine. Several useful nanotechnological applications have been identified in cancer biology, including technologies for the early detection of tumors and cancer biomarkers, and the development of treatment approaches that are impossible to achieve using conventional technologies as demonstrated during the current COVID-19 pandemic, nanotechnology can play a major role in global health. From better screening and diagnostics to therapeutics and vaccines, as well as health monitoring devices, nanotechnology-enabled approaches have the potential of making a tangible impact in the field of infectious diseases. In the area of prevention and treatment of infection, it has been proposed that materials not only be used by professionals (such as during infection treatment by clinicians in hospitals) but also by every person (such as nanoparticles in paints for use at home or over the counter nanodrugs). For this reason, future work must rely on collaboration among engineers, clinicians, and environmental scientists (and those from other fields as well) to fully characterize such nanomaterials in terms of chemistry, impurities, and toxicity. With the establishment of safe usage guidelines, nanomaterials can be safely used for the important and growing area of antimicrobial material design. We should be excited (not frightened) about what the future holds for nanotechnology in these collaborative anti-infection efforts. Despite being a rapidly expanded field of research, the advances of Nanotechnology continue to be largely unknown. Specifically referring to infectious diseases, it would be interesting to explore the level of knowledge of the academic medical community about the contribution of this multidisciplinary science to their prevention and control, which constitutes the main objective of this study.
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