黑色素抗病毒作用与COVID-19大流行的环境相关性及其干预措施

T. Moore, Niyana K. Rasayon
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摘要

2019冠状病毒病大流行对黑色素占主导地位的人群的影响尤为严重,而在非洲大陆,这种新型菌株似乎并未导致人口大量减少。与许多科学预期相反,与世界其他地区的全球感染人数相比,非洲大陆的土著非洲人受到的影响较小。因此,对黑色素和环境的作用的分析应该由关注黑色素显性人群的医疗保健提供者进行评估。有人提出疑问,黑色素具有抗病毒作用,还有来自共病的其他因素影响了制度性种族主义(又名白人至上环境体系)中嵌入的对严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)的易感性。饮食习惯、获得医疗保健、生活方式和遗传都会影响与感染这种毒性冠状病毒相关的疾病的严重程度,因为在遭受过多慢性社会压力的人群中,免疫系统会出现剧烈的不稳定激活。总之,本文将讨论这一危机对非洲人后裔的影响,并建议将替代治疗作为中间手段,而不是完全依赖疫苗作为预防性治疗。鉴于美国的医学史,这种话语的相关性是至关重要的。美国的医学史在以黑色素为主的美国公民中形成了深刻的不信任。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Milieu Relevance of Melanin’s Antiviral Effects and Interventions to the COVID-19 Pandemic
The COVID-19 pandemic has disproportionately affected melanin dominant people, while on the continent of Africa, this novel strain does not appear to have decimated the population. Contrary to many scientific expectations, native Africans on the continent are less impacted compared to the global number of infections in other regions of the world. Therefore, an analysis of the role of melanin and milieu should be assessed by healthcare providers who have a concern for melanin-dominant populations. Questions are raised that Melanin has antiviral effects and there are additional factors derived from comorbidity that impact the susceptibility to Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) embedded in institutional racism (aka the system of white supremacy-Milieu). Dietary practices, access to healthcare, lifestyle and genetics can influence the severity of illnesses associated with contracting this virulent coronavirus via intense erratic activation of the immune system among those subjected to a plethora of chronic societal stressors. In summary, this article will address the effects of this crisis on people of African descent and suggest alternative treatments as an intermediary, rather than exclusive reliance on a vaccine as preventative treatment. The relevance of such discourse is critical given America’s medical history, which has fostered profound distrust among her melanin-dominant citizenry.
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