生态药物警戒:现代环境下的观点、概念、应用和关系

Prachi Khamkar, Debarshi Kar Mahapatra, Atul Kadam
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引用次数: 1

摘要

环境科学家在规范药品废弃物方面取得了长足的进步。然而,对药物引起的新出现的环境问题的监测应该引起药学和药物警戒科学家的进一步关注。生态药物警戒(EPV)作为一种大气药物警戒被广泛认为是减少药物毒素对环境影响的必要手段。方法:在努力回答药物造成的环境问题时,制药部门的建设性参与是必不可少的。在优先的基础上,EPV可以针对个别药物。对于针对药品污染的EPV部署,建议提供某些建议和管理实践解决方案。服药后,某些药物在血液中代谢,变成惰性或转化为代谢物,而其他药物则随尿液或肝脏排出,并随污水排出。排放到排水系统中的物质可以通过污水处理过程加工成许多化学物质。结果:在海洋世界中发现了不同药物及其成分的参与,其中水生环境是迄今为止研究最多的。纳米结构材料已经存在了很长一段时间,它们与生物过程的相互作用已经在各种应用中得到了讨论,以增强对环境和健康影响的理解和重要性。结论:为控制废水中药物残留,应采用污水处理技术。特别是,包括药物警戒专业人员在内的药学人员的存在对于加强多学科合作也很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ecopharmacovigilance: Perspectives, concepts, applications, and relationships in modern context
Introduction: Environmental scientists have made great strides to regulate pharmaceutical waste. However, the monitoring of emerging environmental problems induced by drugs should attract the further interest of pharmacy and pharmacovigilance scientists. Ecopharmacovigilance (EPV) as a kind of pharmacovigilance for the atmosphere is widely recognized as essential to minimize the environmental impact of pharmaceutical toxins. Methods: In efforts to answer the environmental issues created by medications, the constructive involvement of the pharmaceutical sector is essential. On a prioritized basis, EPV can target individual pharmaceuticals. For EPV deployment targeting pharmaceutical contamination, certain advice and management practice solutions are recommended. On administration certain drugs are metabolized throughout the bloodstream, being inert or becoming converted to metabolites, whereas others are excreted in the urine or liver and excreted in the sewage. The substances that are released into drainage can be processed into a number of chemicals by a sewage treatment process. Results: The involvement of different drugs and their components have been found in the marine world, with the aquatic environment being the most researched to date. Nanostructure materials have been around for a long time, and their interactions with biological processes have been discussed in various applications to enhance the understanding and importance of environmental and health effects. Conclusions: In order to regulate pharmaceutical residues in effluents, Technologies for sewage water management should be applied.  In particular, the presence of pharmacy including pharmacovigilance professionals is also important for enhancing multidisciplinary collaboration.
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