萨拉姆叶(Syzygium polyanthum (Wight) Walp)的生物活性

PROCEEDINGS OF THE 4TH INTERNATIONAL SYMPOSIUM ON CURRENT PROGRESS IN MATHEMATICS AND SCIENCES (ISCPMS2018) Pub Date : 2019-11-04 DOI:10.1063/1.5132499

I. D. Dewijanti, W. Mangunwardoyo, N. Artanti, M. Hanafi

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引用次数: 9

摘要

植物是药用化合物的来源。来自桃金娘科的沙兰叶或印度尼西亚月桂叶(Syzygium polyanthum (Wight) Walp)被广泛用作烹饪(烹饪)的草药和香料，以及治疗糖尿病、腹泻和高血压的传统药物。印尼月桂叶含有许多化合物，包括精油、单宁和类黄酮。本研究采用α-葡萄糖苷酶抑制法，对印度尼西亚丹格朗西拉坦省Serpong市科学技术研究中心(PUSPIPTEK)花园月桂叶70%和96%乙醇提取物进行体外抗糖尿病活性测定，并对DPPH自由基进行清除，以测定其抗氧化活性和盐水对虾致死试验(BSLT)毒性。结果表明:70%和96%乙醇提取的月桂叶提取物具有抗糖尿病活性(α-葡萄糖苷酶抑制率分别为97.37%和95.51%)和抗氧化活性(DPPH抑制率分别为89.66%和69.18%)，对盐水对虾幼虫的毒性作用极低(LD50 > 1000µg/mL)。植物是药用化合物的来源。来自桃金娘科的沙兰叶或印度尼西亚月桂叶(Syzygium polyanthum (Wight) Walp)被广泛用作烹饪(烹饪)的草药和香料，以及治疗糖尿病、腹泻和高血压的传统药物。印尼月桂叶含有许多化合物，包括精油、单宁和类黄酮。本研究采用α-葡萄糖苷酶抑制法，对印度尼西亚丹格朗西拉坦省Serpong市科学技术研究中心(PUSPIPTEK)花园月桂叶70%和96%乙醇提取物进行体外抗糖尿病活性测定，并对DPPH自由基进行清除，以测定其抗氧化活性和盐水对虾致死试验(BSLT)毒性。结果表明:70%和96%乙醇提取的月桂叶抗糖尿病活性(α-葡萄糖苷酶抑制率分别为97.37%和95.51%)和抗氧化活性(DPPH抑制率分别为89.66%和69.18%);

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Bioactivities of Salam leaf (Syzygium polyanthum (Wight) Walp)

Plants are source of medicinal compounds. Salam leaf or Indonesian bay leaf (Syzygium polyanthum (Wight) Walp) from the family of Myrtaceae are widely used as herbs and spices for cooking (culinary) and as traditional medicine for diabetes, diarrhea, and hypertension. Indonesian bay leaf contains many compounds including essential oils, tannins, and flavonoids. In this study, 70 % and 96 % ethanol extracts of bay leaf obtained from the garden in Research Center for Science and Technology (PUSPIPTEK), Serpong, Tangerang Selatan, Indonesia were tested in vitro according to α-glucosidase inhibition method to determine antidiabetic activity and to scavenge DPPH free radicals in order to determine antioxidant activity and toxicity on Brine Shrimp Lethality Test (BSLT). The results showed that extraction of Indonesian bay leaf by using 70 % and 96 % ethanol extracts have anti diabetic activity (97.37 % and 95.51 % α-glucosidase inhibition) and antioxidants activities (89.66 % and 69.18 % DPPH inhibition), respectively and have very low toxic effects on brine shrimp larvae (LD50 > 1,000 µg/mL).Plants are source of medicinal compounds. Salam leaf or Indonesian bay leaf (Syzygium polyanthum (Wight) Walp) from the family of Myrtaceae are widely used as herbs and spices for cooking (culinary) and as traditional medicine for diabetes, diarrhea, and hypertension. Indonesian bay leaf contains many compounds including essential oils, tannins, and flavonoids. In this study, 70 % and 96 % ethanol extracts of bay leaf obtained from the garden in Research Center for Science and Technology (PUSPIPTEK), Serpong, Tangerang Selatan, Indonesia were tested in vitro according to α-glucosidase inhibition method to determine antidiabetic activity and to scavenge DPPH free radicals in order to determine antioxidant activity and toxicity on Brine Shrimp Lethality Test (BSLT). The results showed that extraction of Indonesian bay leaf by using 70 % and 96 % ethanol extracts have anti diabetic activity (97.37 % and 95.51 % α-glucosidase inhibition) and antioxidants activities (89.66 % and 69.18 % DPPH inhibition), respe...

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PROCEEDINGS OF THE 4TH INTERNATIONAL SYMPOSIUM ON CURRENT PROGRESS IN MATHEMATICS AND SCIENCES (ISCPMS2018)

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