Brain Metastases Secondary to Advanced Laryngeal Cancer Presenting asDiminution of Vision and Lower Limb Weakness

Objective: Intracranial metastases from primary laryngeal carcinoma are extremely rare and to present as diminution of vision has notbeen reported in published English literature. We present a case of advanced laryngeal carcinoma, who after treatment with surgery andchemo radiation, presented with decreased vision and weakness of lower limbs secondary to brain metastases.Case report: A 35-year-old male presented with dysphonia and L upper neck swelling. Endoscopy revealed a left supraglottic mass withfixed vocal cord and pathology of primary site and neck swelling reported it as moderately differentiated squamous cell carcinoma.Clinical and radiological assessment staged the tumor as T3N2bM0. Patient underwent combined standard surgical and medical treatment.Eight months after completion of treatment patient presented as decreased visual acuity (R > L) and gradually progressing weakness oflower limbs. Evidence of papilloedema on fundus exam prompted an urgent CT brain which showed multiple metastatic deposits in brain.There was no evidence of metastases in lungs, bones or liver.Conclusion: Brain metastases are a known entity in Head and Neck cancer. Larynx as a primary site for the same should be kept inconsideration with an atypical presentation as in present case.