南非人类免疫缺陷病毒感染者城市队列中与身体功能能力相关的因素

R. Roos, H. Myezwa, H. van Aswegen
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引用次数: 2

摘要

背景:人类免疫缺陷病毒(PLWH)感染者的有效疾病管理包括鼓励身体活动。PLWH患者的身体功能能力可能受到多种因素的影响。本研究描述了用6分钟步行测试(6MWT)评估PLWH城市队列的身体功能能力,并确定肺结核史(PTB)、人体测量、年龄和性别是否预测步行距离。方法对84家医院的二手资料进行分析。信息包括6MWT距离、人体测量值和人口统计资料。对数据进行了描述性和推断性统计。回归分析确定了实现6MWT距离的预测因素。p值≤0.05为显著性。结果女性66例(78.6%),男性18例(21.4%),平均年龄39.1(±9.2)岁。该队列的6MWT距离为544.3(±64.4)m,男性步行距离为602.8(±58.6)m,女性步行距离为528.3(±56.4)m;然而,女性经历了更大的努力。大多数样本没有报告PTB病史(n = 67;79.8%)。年龄、性别和人体测量值与6MWT距离相关,但强度低至中等。生成的回归方程包括年龄和性别。该模型具有统计学意义(p < 0.00),占观察到的总方差的34%。结论年龄和性别是运动能力的预测因素,女性运动能力更强。本研究提供了PLWH的物理功能容量信息,并提出了南非PLWH的6MWT参考方程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors associated with physical function capacity in an urban cohort of people living with the human immunodeficiency virus in South Africa
Background Effective disease management for people living with human immunodeficiency virus (PLWH) includes the encouragement of physical activity. Physical function capacity in PLWH may be influenced by a variety of factors. Objectives This study describes the physical function capacity as assessed with the 6-minute walk test (6MWT) of an urban cohort of PLWH and determined whether a history of pulmonary tuberculosis (PTB), anthropometric measures, age and gender predicted distance walked. Method Secondary data collected from 84 PLWH on antiretroviral therapy were analysed. Information included 6MWT distance, anthropometric measurements and demographic profiles. Descriptive and inferential statistics were undertaken on the data. A regression analysis determined predictive factors for 6MWT distance achieved. Significance was set at a p-value of ≤ 0.05. Results The study consisted of 66 (78.6%) women and 18 (21.4%) men with a mean age of 39.1 (± 9.2) years. The 6MWT distance of the cohort was 544.3 (± 64.4) m with men walking further (602.8 [± 58.6] m) than women (528.3 [± 56.4] m); however, women experienced greater effort. The majority of the sample did not report a history of PTB (n = 67; 79.8%). Age, gender and anthropometric measures were associated with 6MWT distance, but of low to moderate strength. The regression equation generated included age and gender. This model was statistically significant (p < 0.00) and accounted for 34% of the total variance observed. Conclusion Age and gender were predictive factors of physical function capacity and women experienced greater effort. Clinical implications This study provides information on the physical function capacity of PLWH and a suggested 6MWT reference equation for PLWH in South Africa.
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