基于1D-CNN步态的帕金森病早期诊断及严重程度评估

Narayan Sharma, Iman Junaid, S. Ari
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引用次数: 0

摘要

步态不规则是医生在诊断时应该考虑的关键迹象之一。然而,步态分析是困难的,并且可能依赖于专家的知识和临床医生的主观性。为了评估步态数据,本研究提出了一种基于深度学习方法的智能尖端系统,用于诊断帕金森病(PD)。所提出的方法分析来自测量虚拟地面反作用力(VGRF)的传感器(连接在脚上)的一维输入。网络的第一部分由18个与系统输入相关的并行id - cnn组成。在第二部分中,18个ID-CNN输出被连接到一个唯一的深度数组中。在第三部分中,使用各种分类器,如支持向量机,多层感知器和随机森林进行最终分类。提出的方法用于两类,即对照组(CO)和PD受试者之间的预测,并根据统一帕金森病评定量表(UPDRS)预测帕金森步态的严重程度。我们的实验表明,该方法在从步态数据中检测PD方面是非常有效的。在Physionet数据集上进行了实验,结果表明所建议的模型在分类结果方面优于其他方法。该模型可以利用步态数据辅助PD的严重程度诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early Diagnosis of Parkinson’s Disease and Severity Assessment based on Gait using 1D-CNN
Gait irregularities are among the crucial signs that doctors should take into account when making a diagnosis. However, gait analysis is difficult and can depend on the knowledge of experts and the clinician’s subjectivity. To assess gait data, this research suggests a smart cutting-edge system, for diagnosis of Parkinson’s disease (PD) based on a deep learning approach. The proposed method analyzes 1-D inputs from sensors (which are connected to foot) that measure the virtual ground reaction force (VGRF). The first section of the network is composed of eighteen parallel ID-CNNs that correlate to the system’s inputs. In the second section, the eighteen number of ID-CNN outputs are concatenated into one unique deep array. In the third section, various classifiers such as support vector machine, multi-layer perceptron and random forest are used for final classification. The proposed methodology is used to predict between the two classes, i.e., control (CO) and PD subjects, as well as to predict the severity of Parkinson’s gait according to the Unified Parkinson’s Disease Rating Scale (UPDRS). Our test shows that the suggested method is highly effective in detecting PD from gait data. Experiments were conducted on the Physionet dataset, and the results specify that the suggested model outperforms alternative methods in terms of classification outcomes. This model can assist in the severity diagnosis of PD by using gait data.
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