9经导管主动脉瓣植入术后次日出院

J. Bates-Powell, Sophie Z Gu, R. Edwards, A. Zaman
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摘要

经导管主动脉瓣植入术(TAVI)越来越多地应用于严重症状性主动脉瓣狭窄患者。很少有研究关注住院时间(LOS)和次日出院的可行性。本研究旨在评估TAVI术后次日出院的可行性和相关因素,以帮助选择合适的患者进入TAVI“快速通道”入院途径。方法收集2014年1月至2019年3月在我们中心进行的所有TAVI手术的数据,并对其进行回顾性分析。将TAVI术后1天内出院的患者(早出院组)与连续24小时后出院的患者(晚出院组)进行比较。衰弱程度采用加拿大健康与老龄化研究(CSHA)衰弱量表评估,基线功能状态采用Katz日常生活活动独立性指数评估。结果502例患者中,男性274例(54.6%),平均年龄(83.2±7.3)岁,CSHA衰弱量表体弱者87例(17.7%)。中位Katz指数为6(即功能独立,四分位间距[IQR] 1),平均logistic Euroscore为17.4±10.7。468例(95.5%)采用经皮经股通路,64例(14.4%)采用全身麻醉。出院前早期并发症与国家标准相当:死亡11例(2.3%),心肌梗死1例(0.2%),PPM 20例(4.3%),胃肠道出血3例(0.6%),填塞5例(1.1%)。术后LOS中位数为2 (IQR 3)天,总住院时间中位数为3 (IQR 5)天。早期出院213例(44.7%)。多因素logistic回归分析显示男性(优势比[OR]: 2.81, 95%可信区间[CI]: 1.68 ~ 4.7;结论近半数患者TAVI术后次日出院。基线时症状最小的年轻男性患者(NYHA利益冲突无
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9 Next-day discharge after transcatheter aortic valve implantation
Introduction Transcatheter aortic valve implantation (TAVI) is being used increasingly in patients with severe symptomatic aortic stenosis. Few studies focused on hospital length of stay (LOS) and feasibility of next-day discharge. This study aims to evaluate the feasibility and factors associated with next-day discharge post TAVI, which can be used to help selecting suitable patients for a ‘fast-track’ TAVI admission pathway. Methods Data from all TAVI procedures conducted at our centre from January 2014 to March 2019 were collected in our local TAVI registry, and analysed retrospectively. Patients discharged within 1 day of TAVI (early discharge group) were compared with consecutive patients discharged after 24 hours (late discharge group). Degree of frailty was assessed by the Canadian Study of Health and Aging (CSHA) frailty scale, and baseline functional status was assessed by Katz index of independence in activities of daily living. Results Of 502 patients, 274 (54.6%) were male, mean age 83.2±7.3 years, and 87 (17.7%) patients were considered frail by CSHA frailty scale. Median Katz index was 6 (i.e. functionally independent, interquartile range [IQR] 1), and mean logistic Euroscore 17.4±10.7. Percutaneous transfemoral access was performed in 468 (95.5%), and general anaesthesia was used in 64 (14.4%) patients. Early complications before discharge were comparable to national standards: death in 11 (2.3%), MI in 1 (0.2%), PPM in 20 (4.3%), gastrointestinal bleed in 3 (0.6%), and tamponade in 5 (1.1%). Median LOS post procedure was 2 (IQR 3) days, median length of total hospital stay was 3 (IQR 5) days. Early discharge was achieved in 213 (44.7%) patients. Multivariate logistic regression analysis showed that male gender (odds ratio [OR]: 2.81, 95% confidence interval [CI]: 1.68 to 4.7; p Conclusions Next-day discharge after TAVI can be achieved in nearly half of all patients. Male younger patients with minimal symptoms at baseline (NYHA Conflict of Interest None
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