包含假结的RNA结构预测算法与方案

Zhendong Liu, Fanghan Liu, Qingxia Kong, Fanchang Hao, Hongluan Zhao
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引用次数: 0

摘要

基于RNA折叠结构的特点,我们研究了RNA的伪结结构,并将盆跳图作为RNA折叠景观结构的一种新模型。本文设计了一种1+ε (ε>0)多项式时间逼近方案来搜索最大堆叠数,并在RNA伪结结构中给出了该逼近方案的证明。提出了基于BHG的屏障树的计算算法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Algorithm and Scheme in RNA Structure Prediction Including Pseudoknots
It is an NP-hard problem for prediction of RNA folding structure incuding pseudoknots, we investigate the RNA pseudoknotted structure based on characteristics of the RNA folding structure, and the Basin Hopping Graph as a novel model of RNA folding landscape structures. Our paper design an 1+ε (ε>0) polynomial time approximation scheme in searching maximum number of stackings, we give the proof of the approximation scheme in RNA pseudoknotted structure. we have also presented the computing algorithm of barrier tree based on the BHG.
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