自发性脑动静脉畸形闭塞

D. Shchehlov, O. Svyrydiuk, S.V. Chebanyuk, O. Slobodian, M. Vyval
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引用次数: 1

摘要

自发闭塞的动静脉畸形(AVM),其特点是完全消失的动静脉病灶和早期静脉引流,是一种罕见的。这种现象发生的频率从0.1%到1.3%不等。我们分析了两例自发性脑动静脉闭塞患者,分别为28岁和40岁女性,术后3年和13年无出血。在这两例中,由于头痛,在常规神经影像学中诊断出AVM。两例患者均有浅表小畸形。在讨论了手术治疗的风险后,两名患者都拒绝进行任何干预。诊断后3年进行血管造影,随访病程,发现AVM完全消失。另一名患者3年后头痛持续消退。确诊后13年进行随访血管造影,并确认自发性AVM闭塞。鉴于自发性闭塞后疾病复发的数据,这类患者需要长期随访。当动静脉畸形破裂时,血流动力学变化可以解释畸形的血栓形成,但未破裂的动静脉畸形自发闭塞的机制尚不清楚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spontaneous occlusion of the cerebral arteriovenous malformations
Spontaneous occlusion of arteriovenous malformations (AVM), characterized by complete disappearance of the AVM nidus and early venous drainage, and is a rare. The frequency of this phenomenon varied from 0.1 to 1.3 %.We analyzed two cases of spontaneous occlusion of cerebral AVMs with a non-hemorrhagic debut after 3 and 13 years in women aged 28 and 40 years, respectively. In both cases AVM was diagnosed during routine neuroimaging because of headache. Both patients had superficial small malformations. After discussing the risks of surgical treatment, both patients refused to perform any intervention. Scheduled angiography was performed 3 years after the diagnosis to follow-up the course of the disease and revealed complete disappearance of the AVM. Another patient noted persistent regression of headache after 3 years. Follow-up angiography was performed 13 years after diagnosis and confirmed spontaneous occlusion of the AVM. Given the data on the recurrence of the disease after spontaneous occlusion, such patients require long-term follow-up.When an AVM ruptures, hemodynamic changes may explain the thrombosis of the malformation, but the mechanisms of spontaneous occlusion in non-ruptured AVM remain unclear.
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