一种基于铜纳米簇的过氧化氢和葡萄糖的新型灵敏检测方法

Shuqi Zhou, Xinyi Wang, Liubing Kong, Wen-Hui Lin, Chiyu Ma, Xianyou Sun, Zhuoru Huang, K. Ying, H. Wan, Ping Wang
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引用次数: 0

摘要

血液或尿液中的葡萄糖水平是糖尿病的重要指标。本文以巯基琥珀酸修饰铜纳米团簇(MSA-CuNCs)为基础,建立了一种灵敏、简便的比色测定方法。msa - cccs作为双氧水催化剂和显色试剂。在520 nm处观察吸收,可以检测到H2O2,检测范围为0.2 ~ 5mm,检出限为0.05 mM,葡萄糖氧化酶也可以检测到葡萄糖,检测范围为0.2 ~ 5mm,检出限为0.12 mM,这种简单、经济的方法具有很大的临床应用潜力
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel and Sensitive Detection Method of Hydrogen Peroxide and Glucose Based on Copper Nanoclusters
The level of glucose in blood or urine are an important indicator of diabetes. Here, a sensitive and easily operated colorimetric methods was established based on the mercaptosuccinic acid modified copper nanocluster(MSA-CuNCs). MSA-CuNCs, which was act as both thehydrogen peroxide catalyst and the chromogenic reagent. By observing the absorption at 520 nm, the H2O2 could be detected, with the detection range of 0.2-5 mM and the detection limit of 0.05 mM. Using glucose oxidase, the glucose could also be detected, the detection range was 0.2-5 mM with the detection limit of 0.12 mM. This simple and cost-effective approach indicating its great potential for point-of-care applications
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