血液粘度与组织灌注的关系

D. Cerutti, J. Fernández, I. Schein
{"title":"血液粘度与组织灌注的关系","authors":"D. Cerutti, J. Fernández, I. Schein","doi":"10.24875/raa.20000016","DOIUrl":null,"url":null,"abstract":"Background: Hemorrhagic shock is one of the leading causes of death in the surgical and polytraumatized patient. The central goal: Of every reanimation maneuvers is to bring oxygen to the cells, requiring an adequate management of macro and micro hemodynamic variables. The blood viscosity, one of these variables, plays a very important role. Methods: An experimental study was carried out with 10 pigs which were randomly divided in two groups. Both groups were exanguinated to a 70% of their blood volume. In the first group, named Group H, the fluid reposition was made with HES, while in the second group, named Group S, was made with autologous blood. Hourly assessment of macro and micro hemodynamic variables, and plasmatic viscosity, was carried out for six hours. Results: The results obtained were individually analyzed. Lactate, central venous oxygen saturation and bases exces values were taken to measure tissue perfusion. These values were reflected in tables and figures, and were analyzed together with the viscosity of the swine blood. Conclusions: On the basis of the results of ours measurements we can infer that the tissue perfusion was better when the maintenance of plasmatic and, secondarily, blood viscosity values were prioritize over the hematocrit level. However more studies are needed to confirm this theory.","PeriodicalId":351025,"journal":{"name":"Revista Argentina de Anestesiologia","volume":"26 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relación entre la viscosidad sanguínea y la perfusión tisular\",\"authors\":\"D. Cerutti, J. Fernández, I. Schein\",\"doi\":\"10.24875/raa.20000016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Hemorrhagic shock is one of the leading causes of death in the surgical and polytraumatized patient. The central goal: Of every reanimation maneuvers is to bring oxygen to the cells, requiring an adequate management of macro and micro hemodynamic variables. The blood viscosity, one of these variables, plays a very important role. Methods: An experimental study was carried out with 10 pigs which were randomly divided in two groups. Both groups were exanguinated to a 70% of their blood volume. In the first group, named Group H, the fluid reposition was made with HES, while in the second group, named Group S, was made with autologous blood. Hourly assessment of macro and micro hemodynamic variables, and plasmatic viscosity, was carried out for six hours. Results: The results obtained were individually analyzed. Lactate, central venous oxygen saturation and bases exces values were taken to measure tissue perfusion. These values were reflected in tables and figures, and were analyzed together with the viscosity of the swine blood. Conclusions: On the basis of the results of ours measurements we can infer that the tissue perfusion was better when the maintenance of plasmatic and, secondarily, blood viscosity values were prioritize over the hematocrit level. However more studies are needed to confirm this theory.\",\"PeriodicalId\":351025,\"journal\":{\"name\":\"Revista Argentina de Anestesiologia\",\"volume\":\"26 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Argentina de Anestesiologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24875/raa.20000016\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Argentina de Anestesiologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24875/raa.20000016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:失血性休克是外科和多发创伤患者死亡的主要原因之一。中心目标:每一次复苏操作都是为了给细胞提供氧气,这需要对宏观和微观血液动力学变量进行适当的管理。血液粘度,这些变量之一,起着非常重要的作用。方法:选用10头猪,随机分为2组进行试验研究。两组都被检查到70%的血容量。第一组(H组)采用HES置换液,第二组(S组)采用自体血置换液。每小时评估宏观和微观血流动力学变量和血浆粘度,持续6小时。结果:分别对所得结果进行分析。取乳酸、中心静脉血氧饱和度及基准值测量组织灌注。这些数值以表格和图表的形式反映出来,并与猪血的粘度一起进行分析。结论:根据我们的测量结果,我们可以推断,当血浆和血液粘度值的维持优先于红细胞压积水平时,组织灌注更好。然而,需要更多的研究来证实这一理论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relación entre la viscosidad sanguínea y la perfusión tisular
Background: Hemorrhagic shock is one of the leading causes of death in the surgical and polytraumatized patient. The central goal: Of every reanimation maneuvers is to bring oxygen to the cells, requiring an adequate management of macro and micro hemodynamic variables. The blood viscosity, one of these variables, plays a very important role. Methods: An experimental study was carried out with 10 pigs which were randomly divided in two groups. Both groups were exanguinated to a 70% of their blood volume. In the first group, named Group H, the fluid reposition was made with HES, while in the second group, named Group S, was made with autologous blood. Hourly assessment of macro and micro hemodynamic variables, and plasmatic viscosity, was carried out for six hours. Results: The results obtained were individually analyzed. Lactate, central venous oxygen saturation and bases exces values were taken to measure tissue perfusion. These values were reflected in tables and figures, and were analyzed together with the viscosity of the swine blood. Conclusions: On the basis of the results of ours measurements we can infer that the tissue perfusion was better when the maintenance of plasmatic and, secondarily, blood viscosity values were prioritize over the hematocrit level. However more studies are needed to confirm this theory.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信