{"title":"流式细胞术分析低频脉冲电磁场(7Hz, 30mT)对培养H4胶质瘤细胞活力的影响","authors":"J. Kaszuba-Zwoińska, B. Nowak, P. Guzdek, K. Gil","doi":"10.23919/EMF-MED.2018.8526058","DOIUrl":null,"url":null,"abstract":"Glioma is a human lethal malignancy with worldwide range. Current achievements in surgery, radiotherapy, chemotherapy, targeting therapy are still not effective and the disease remains one of the most lethal malignancies. The improvement of glioma treatment efficacy is desired. Aim of our studies was to investigate viability changes in H4 glioma cell line induced by low frequency pulsed electromagnetic field (LF-PEMF; 7Hz, 30mT) exposure, analyzed by flow cytometry. Obtained results have found out, that LF-PEMF stimulation of H4 glioma cell cultures induced apoptosis in exposed cells.","PeriodicalId":134768,"journal":{"name":"2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Cell viability changes in cultured H4 glioma cells upon low frequency pulsed electromagnetic field (7Hz, 30mT) exposure in flow cytometry analysis\",\"authors\":\"J. Kaszuba-Zwoińska, B. Nowak, P. Guzdek, K. Gil\",\"doi\":\"10.23919/EMF-MED.2018.8526058\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Glioma is a human lethal malignancy with worldwide range. Current achievements in surgery, radiotherapy, chemotherapy, targeting therapy are still not effective and the disease remains one of the most lethal malignancies. The improvement of glioma treatment efficacy is desired. Aim of our studies was to investigate viability changes in H4 glioma cell line induced by low frequency pulsed electromagnetic field (LF-PEMF; 7Hz, 30mT) exposure, analyzed by flow cytometry. Obtained results have found out, that LF-PEMF stimulation of H4 glioma cell cultures induced apoptosis in exposed cells.\",\"PeriodicalId\":134768,\"journal\":{\"name\":\"2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med)\",\"volume\":\"5 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23919/EMF-MED.2018.8526058\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23919/EMF-MED.2018.8526058","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cell viability changes in cultured H4 glioma cells upon low frequency pulsed electromagnetic field (7Hz, 30mT) exposure in flow cytometry analysis
Glioma is a human lethal malignancy with worldwide range. Current achievements in surgery, radiotherapy, chemotherapy, targeting therapy are still not effective and the disease remains one of the most lethal malignancies. The improvement of glioma treatment efficacy is desired. Aim of our studies was to investigate viability changes in H4 glioma cell line induced by low frequency pulsed electromagnetic field (LF-PEMF; 7Hz, 30mT) exposure, analyzed by flow cytometry. Obtained results have found out, that LF-PEMF stimulation of H4 glioma cell cultures induced apoptosis in exposed cells.
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