基于等几何分析的混合多尺度肿瘤生长模型的研究

Paulo Wander Barbosa, Adriano M. de A. Cirtes, L. Catabriga
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引用次数: 1

摘要

这项工作提出了一个混合和多尺度模型的实验考虑无血管和血管肿瘤的生长。该模型采用相场方程来描述肿瘤和血管的生长,用反应扩散方程来描述营养物质和血管生成因子的分布。我们使用基于等几何分析的高性能框架PetIGA来实现模型。我们的数值实验表明,该模型能够表征毛细血管网络的形成及其表征特定肿瘤生长构型的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Studies of a Hybrid and Multiscale Tumor Growth Model via Isogeometric Analysis using PetIGA
This work presents experiments considering a hybrid and multiscale model of avascular and vascular tumor growth. The model uses phase-field equations to describe the tumor and vascular growth, and reaction-diffusion equations for the distribution of nutrients and angiogenic factors. We use the high-performance framework PetIGA based on Isogeometric Analysis to implement the model. Our numerical experiments show that the model is able to represent the capillary network formation and its ability to represent specific tumor growth configurations.
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