弓形虫病所致嗜酸性粒细胞性肺炎:一例罕见儿科病例报告及文献复习

Luiza Fonseca Sandes Fernandes, Isabele Santos Piuzana Barbosa, Juliana Campos Rodrigues Fossa, Larissa Alvim Werner, Luana Amaral Magalhães de Souza Lima, Pedro Celeste Valadares, Mariana Isadora Ribeiro Vieira
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引用次数: 0

摘要

人类弓形虫病是一种由弓形虫属寄生虫幼虫引起的人畜共患病。它通常是无症状和自限性的。然而,由于寄生虫的直接作用或免疫机制,它可影响多个器官,导致许多临床表现。在儿科患者中,20-85%的内脏弓形虫病病例累及肺部,表现为Löffler综合征、慢性肺炎、嗜酸性肺炎或婴儿喘息综合征。由于其罕见性,由于弓形虫幼虫嗜酸性肺炎在医疗记录中没有很好的记录。本文报告一个2岁儿童的临床病例,每日摄入沙子和泥土,随后出现突发性肺部症状,9天发烧,胸部x线异常和强烈的外周嗜酸性粒细胞增多。由于怀疑弓形虫病肺炎,经过一系列实验室检查,诊断为由寄生虫引起的嗜酸性肺炎。阿苯达唑治疗5天后,患者呼吸道症状进行性改善,外周血嗜酸性粒细胞减少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Eosinophilic Pneumonia Due to Toxocariasis: A Rare Case Report in a Paediatric Patient and Literature Review
Human toxocariasis is a zoonosis caused by the larvae of Toxocara genus parasites. It is usually asymptomatic and self-limiting. However, due to either the direct action of parasites or by immunological mechanisms, it can affect several organs resulting in many clinical manifestations. Among paediatric patients, lung involvement occurs in 20–85% of cases of visceral toxocariasis, as Löffler’s syndrome, chronic pneumonia, eosinophilic pneumonia, or baby wheezing syndrome. Because of its rarity, eosinophilic pneumonia due to Toxocara larvae is not well-documented amongst medical records. This article presents a clinical case of a 2-year-old with a history of daily sand and soil ingestion, followed by sudden pulmonary symptoms, 9-day fever, abnormal chest X-ray, and intense peripheral eosinophilia. Due to the suspicion of toxocariasis pneumonia after a series of laboratory tests, the diagnosis of eosinophilic pneumonia caused by the parasite was confirmed. After treatment with albendazole for 5 days, the patient displayed progressive improvement in respiratory symptoms and a reduction in peripheral eosinophilia.
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