墨西哥COVID-19实体器官移植受者的情况

José Salvador Aburto-Morales, José André Madrigal-Bustamante, Josefina Romero-Méndez, Cinthya Ayerim Lucio-García
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引用次数: 0

摘要

导语:接受免疫抑制剂治疗的移植患者感染COVID-19的风险更高,其发展过程中出现并发症的风险更高,同时移植器官排斥的可能性也更高,而且难以预防、及时发现、监测和控制。在墨西哥病例中,确定获得COVID-19疾病的移植受者的状态和演变具有重要意义。材料和方法:这是一项横断面研究,其信息于2020年4月1日至5月25日在墨西哥收集。从主要信息来源对简单频率和相对频率(比率、比例和比率)进行描述性分析,以确定COVID-19移植受者的一般特征。结果:移植受者中报告新冠肺炎确诊病例28例。其中,大多数发生在男性(57.14%)、墨西哥城(78.57%)、卫生部机构(46.43%)和肾移植(92.86%)。受影响最大的年龄组是45-64岁。在所有病例中,有8例死亡,据估计病死率为28.6%。结论:这些数据可能表明,与墨西哥普通人群相比,实体器官移植受者的COVID-19疾病病程可能更严重。所产生的信息是SNDT的专业人员和成员处理这一流行病并更好地了解其模式的相关工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Situación de los receptores de trasplante de órganos sólidos con COVID-19 en México
Introduction: Transplanted patients who receive immunosuppressants are at a higher risk of getting COVID-19 infection, of presenting complications in its evolution and the concomitant probability of rejection of the transplanted organ, besides the difficulties for its prevention, prompt detection, monitoring and control. It is relevant to identify the status and evolution of transplant recipients who acquired COVID-19 disease in the Mexican case. Material and methods: It is a cross-sectional study, for which information was collected between April 1 and May 25, 2020 in Mexico. A descriptive analysis of simple and relative frequencies as ratios, proportions and rates was performed from primary sources of information, to identify the general characteristics of the recipients of transplantation with COVID-19. Results: 28 confirmed cases of COVID-19 were reported in transplant recipients. Of these, the majority occurred in men (57.14%), in recipients from Mexico City (78.57%), in facilities from the Ministry of Health (46.43%) and corresponded to kidney transplantation (92.86%). The most affected age group was 45-64 years. Of the total cases, eight died, it has been estimated a case fatality of 28.6%. Conclusions: The data may suggest that COVID-19 disease in solid organ transplant recipients could have a more severe course compared to the general Mexican population. The information generated is a relevant tool for professionals and members of SNDT to approach to this epidemic and to have a better understand about its pattern.
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