{"title":"尼日利亚南部三级医院老年糖尿病患者的合理用药情况","authors":"W. Ojieabu, P. Erah","doi":"10.46881/ajsn.v6i0.150","DOIUrl":null,"url":null,"abstract":"International Diabetes Foundation puts Nigeria's national diabetes prevalence rate at 3.9% in year 2013. Number of drugs per patient is the main factor associated with adverse reactions among elderly patients. Objective was to evaluate prescription pattern for elderly diabetic patients. This was descriptive prospective study of 150 case files of older patients diagnosed with type 2 diabetes and receiving treatment in the endocrinology clinic of Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State. Data collected included socio-demographic characteristics and pattern of prescribed medications. Data were analyzed with SPSS version 16. P 0.05 was considered significant. Mean age of the group was 65.8±10.0 years. Metformin was the most frequently prescribed (81.3%) and in combination of other antidiabetics, the highest being that with Metformin+Pioglitazone+ Glimepiride (18%). The most commonly prescribed anti hypertensives was lisinopril/Ramipril (50.0%). Mean number of drugs per prescription was 6.0. Patients mostly encountered a range of 5-7 drugs per prescription (63.3%). Drugs prescribed in generics and from essential drug list were significantly lower than the recommended WHO values (p >0.05). The findings indicate that the prescribing pattern could be said to be in compliant with our treatment guidelines although not in line with WHO's recommendations.","PeriodicalId":120574,"journal":{"name":"African Journal of Science and Nature","volume":"26 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"RATIONAL USE OF MEDICINES AMONGST ELDERLY DIABETIC PATIENTS IN A TERTIARY HOSPITAL IN SOUTHERN NIGERIA\",\"authors\":\"W. Ojieabu, P. Erah\",\"doi\":\"10.46881/ajsn.v6i0.150\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"International Diabetes Foundation puts Nigeria's national diabetes prevalence rate at 3.9% in year 2013. Number of drugs per patient is the main factor associated with adverse reactions among elderly patients. Objective was to evaluate prescription pattern for elderly diabetic patients. This was descriptive prospective study of 150 case files of older patients diagnosed with type 2 diabetes and receiving treatment in the endocrinology clinic of Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State. Data collected included socio-demographic characteristics and pattern of prescribed medications. Data were analyzed with SPSS version 16. P 0.05 was considered significant. Mean age of the group was 65.8±10.0 years. Metformin was the most frequently prescribed (81.3%) and in combination of other antidiabetics, the highest being that with Metformin+Pioglitazone+ Glimepiride (18%). The most commonly prescribed anti hypertensives was lisinopril/Ramipril (50.0%). Mean number of drugs per prescription was 6.0. Patients mostly encountered a range of 5-7 drugs per prescription (63.3%). Drugs prescribed in generics and from essential drug list were significantly lower than the recommended WHO values (p >0.05). The findings indicate that the prescribing pattern could be said to be in compliant with our treatment guidelines although not in line with WHO's recommendations.\",\"PeriodicalId\":120574,\"journal\":{\"name\":\"African Journal of Science and Nature\",\"volume\":\"26 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-06-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"African Journal of Science and Nature\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46881/ajsn.v6i0.150\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Journal of Science and Nature","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46881/ajsn.v6i0.150","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
国际糖尿病基金会(International Diabetes Foundation)估计,2013年尼日利亚全国糖尿病患病率为3.9%。患者人均用药数量是影响老年患者不良反应的主要因素。目的探讨老年糖尿病患者的处方模式。这是一项描述性前瞻性研究,研究对象是在奥贡州Sagamu的奥拉比西奥纳班乔大学教学医院内分泌科门诊诊断为2型糖尿病并接受治疗的150例老年患者。收集的数据包括社会人口学特征和处方药物的模式。数据采用SPSS version 16进行分析。P < 0.05认为差异有统计学意义。患者平均年龄65.8±10.0岁。二甲双胍是最常见的处方(81.3%),并与其他抗糖尿病药物联合使用,最高的是二甲双胍+吡格列酮+格列美脲(18%)。最常用的抗高血压药物是赖诺普利/雷米普利(50.0%)。每张处方的平均药物数为6.0种。患者在每张处方中最多遇到5-7种药物(63.3%)。非专利药和基本药物目录中使用的药物显著低于WHO推荐值(p >0.05)。调查结果表明,处方模式可以说符合我们的治疗指南,尽管不符合世卫组织的建议。
RATIONAL USE OF MEDICINES AMONGST ELDERLY DIABETIC PATIENTS IN A TERTIARY HOSPITAL IN SOUTHERN NIGERIA
International Diabetes Foundation puts Nigeria's national diabetes prevalence rate at 3.9% in year 2013. Number of drugs per patient is the main factor associated with adverse reactions among elderly patients. Objective was to evaluate prescription pattern for elderly diabetic patients. This was descriptive prospective study of 150 case files of older patients diagnosed with type 2 diabetes and receiving treatment in the endocrinology clinic of Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State. Data collected included socio-demographic characteristics and pattern of prescribed medications. Data were analyzed with SPSS version 16. P 0.05 was considered significant. Mean age of the group was 65.8±10.0 years. Metformin was the most frequently prescribed (81.3%) and in combination of other antidiabetics, the highest being that with Metformin+Pioglitazone+ Glimepiride (18%). The most commonly prescribed anti hypertensives was lisinopril/Ramipril (50.0%). Mean number of drugs per prescription was 6.0. Patients mostly encountered a range of 5-7 drugs per prescription (63.3%). Drugs prescribed in generics and from essential drug list were significantly lower than the recommended WHO values (p >0.05). The findings indicate that the prescribing pattern could be said to be in compliant with our treatment guidelines although not in line with WHO's recommendations.