食管神经内分泌肿瘤1例

Letícia Mocellin, Eduarda Paitl Agostinho, Vinicius beck da Silveira, M. Gonçalves, João Alfredo Diedrich Neto
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摘要

简介:神经内分泌肿瘤,也称为神经内分泌癌,是在神经内分泌系统的任何区域形成的肿瘤。虽然它们在胃肠道中更常见(67.5%),但在食道中出现却很少见。它的另一个重要特点是生长缓慢,攻击性低。病例报告:一名46岁男性患者,因进行性吞咽合并固体性脊索狭窄求医,消化内镜检查诊断为食管远端,解剖及免疫组化检查为神经内分泌性食管肿瘤。受分期影响,腹腔干有大量肝转移和淋巴结肿大,选择姑息治疗。患者病情发展不利,进展为黄疸、腹水,一般情况恶化,诊断后约3个月死亡。讨论:自1970年以来,由于诊断技术的现代化,神经内分泌食管癌的发病率和患病率一直在增加。尽管诊断能力有所提高,但这种病理仍然很少见,约占食管癌的0.15% - 2.80%。该肿瘤患者的中位生存时间为22.4个月,与其他消化道神经内分泌肿瘤的发展完全不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Esophageal Neuroendocrine Tumor: Case Report
Introduction: Neuroendocrine tumors, also called neuroendocrine carcinomas, are those that form in any region of the neuroendocrine system. Although they are more common in the gastrointestinal tract (67.5%), their appearance in the esophagus is rare. Another important characteristic is its slow growth and low degree of aggressiveness. Case report: A46-year-old male patient, seeking care for progressive phagia for solidspathstenoses digestive endoscopy that showed the diagnosis of distal esophagus whose anatomoological and immunohistochemical was of a neuroendocrine esophageal tumor. Subjected to staging, there were numerous liver metastases and lymph node enlargement of the celiac trunk, and palliative treatment was chosen. The patient had an unfavorable evolution, progressing to jaundice, ascites, worsening of general condition, progressed to death in about 3 months after diagnosis. Discussion: The incidence and prevalence of neuroendocrine esophageal tumor has been increasing since 1970 due to the modernization of diagnostic techniques. Despite the increase in diagnostic capacity, this pathology remains rare, corresponding to 0.15% - 2.80% of esophageal carcinomas. The median survival time for patients with this neoplasm is 22.4 months, having a totally different evolution from other neuroendocrine tumors of the digestive tract..
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