【急性肠系膜血管闭塞:病理生理、临床分期、诊断】。

G W Hagmüller
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引用次数: 0

摘要

老年和心血管疾病导致SMA闭塞。休克是由肠缺血引起并维持的。由于乳酸是厌氧糖酵解的最终产物,乳酸中毒是一个有价值的临床参数。乳酸值高于4-5 mmol/l是急性SMA闭塞症状存在的确凿证据。II期和III期的生存机会很低,伴有晚期休克和不可逆转的坏疽。SMA血运重建结合适当的肠切除术可减少肠粘膜中有毒和致死物质的产生,从而增加生存机会。血清乳酸的测定应该是诊断过程中不可缺少的一部分,密切的随访既是肠缺血等级的适当指标,也是评估是否需要再次检查的一种手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Acute mesenteric vascular occlusion: pathophysiology, clinical stages, diagnosis].

Advanced age and cardiovascular diseases cause of SMA occlusion. Shock is triggered and maintained by bowel ischemia. Since lactate is the end product of anaerobic glycolysis, lactacidosis is a valuable clinical parameter. Lactate values above 4-5 mmol/l are conclusive evidence in the presence of symptoms of acute SMA occlusion. Chance of survival are poor in stages II and III with advanced shock and non reversible gangrene. Revascularisation of the SMA combined with adequate bowel resection reduces the production of toxic and lethal substances in the intestinal mucosa, thus increasing the chance of survival. Determination of serum lactate should be an integral part of the diagnostic procedure and the close followup for it is both an adequate index of the grade of intestinal ischemia and a means of assessing whether a second-look is warranted.

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