Carl G. Gahmberg, Pekka Nortamo, Carmela Kantor, Matti Autero, Pekka Kotovuori, Leena Hemiö, Rosalba Salcedo, Manuel Patarroyo
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The pivotal role of the Leu-CAM and ICAM molecules in human leukocyte adhesion
Cellular adhesion is of fundamental importance in leukocyte physiology. It is a complex, strictly regulated process, which involves the participation of several cell surface glycoproteins. Among the most important are the Leu-CAMs or the DC11 / CD18 integrin receptors, and their adhesion ligands ICAM-1 (CD54) and ICAM-2. In this review we summarize some recent work on various aspects of these molecules.
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