{"title":"[半胱氨酸对乙醇肝损伤大鼠肝脏蛋白质代谢的影响]。","authors":"E Skrzydlewska, K Worowski, L Chyczewski","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Rats intoxicated with ethanol at the dose of 0.6 g/100 g of the body weight during 4 weeks were fed on standard diet and the one containing 0.125, 0.25 and 0.5% L-cysteine. Intoxication of rats fed standard food causes an increase in the activity of cathepsin D and gamma-glutamyl-transpeptidase in the liver and an increase in the activity of alanine aminotransferase and gamma-glutamyl-transpeptidase in the blood serum. Consuming by rats food containing small and medium quantity of cysteine causes normalization of the activity of all enzymes, whereas consuming food containing large quantity of cysteine does not give such effect.</p>","PeriodicalId":77367,"journal":{"name":"Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis","volume":"35-36 ","pages":"129-41"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Effect of cysteine on protein metabolism in the liver of rats with ethanol-induced liver damage].\",\"authors\":\"E Skrzydlewska, K Worowski, L Chyczewski\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rats intoxicated with ethanol at the dose of 0.6 g/100 g of the body weight during 4 weeks were fed on standard diet and the one containing 0.125, 0.25 and 0.5% L-cysteine. Intoxication of rats fed standard food causes an increase in the activity of cathepsin D and gamma-glutamyl-transpeptidase in the liver and an increase in the activity of alanine aminotransferase and gamma-glutamyl-transpeptidase in the blood serum. Consuming by rats food containing small and medium quantity of cysteine causes normalization of the activity of all enzymes, whereas consuming food containing large quantity of cysteine does not give such effect.</p>\",\"PeriodicalId\":77367,\"journal\":{\"name\":\"Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis\",\"volume\":\"35-36 \",\"pages\":\"129-41\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
按0.6 g/100 g体重的乙醇浓度灌胃4周,分别饲喂标准日粮和含0.125、0.25和0.5% l -半胱氨酸的日粮。饲喂标准食物的中毒大鼠肝脏组织蛋白酶D和γ -谷氨酰转肽酶活性增加,血清丙氨酸转氨酶和γ -谷氨酰转肽酶活性增加。大鼠食用含有中、少量半胱氨酸的食物可使所有酶的活性恢复正常,而食用含有大量半胱氨酸的食物则没有这种作用。
[Effect of cysteine on protein metabolism in the liver of rats with ethanol-induced liver damage].
Rats intoxicated with ethanol at the dose of 0.6 g/100 g of the body weight during 4 weeks were fed on standard diet and the one containing 0.125, 0.25 and 0.5% L-cysteine. Intoxication of rats fed standard food causes an increase in the activity of cathepsin D and gamma-glutamyl-transpeptidase in the liver and an increase in the activity of alanine aminotransferase and gamma-glutamyl-transpeptidase in the blood serum. Consuming by rats food containing small and medium quantity of cysteine causes normalization of the activity of all enzymes, whereas consuming food containing large quantity of cysteine does not give such effect.