应胃方对不同证型2型糖尿病患者下肢血管病变的影响

Li Ruiyu, Li Yue, L. Xing, L. Meng, Zhang Chenyu, L. Qingwen, Hou Jinjie
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引用次数: 0

摘要

目的:探讨颖维方治疗2型糖尿病合并下肢血管病患者踝肱指数(ABI)及足背动脉峰值流速的变化。方法:观察2型糖尿病合并下肢血管病变36例,其中阴虚热证13例,气阴虚证9例,阴阳虚证14例。口服“应胃方”胶囊,每次5粒,每日3次,结合中医辨证论治,常规治疗低血糖等。治疗150 d后与治疗前比较,测定踝肱指数(ankle-brachial index, ABI)和足背动脉血流峰值速率的变化。结果:治疗后糖尿病下肢血管病患者足背动脉ABI、血流峰值速率均有不同程度改变(P < 0.05、P<0.01), ABI改善更为明显(P <0.01)。气阴虚证和阴阳虚证也有改善(P<0.05)。气阴虚证与阴虚证治疗后干热比较(P<0.05);结论:应胃方能显著改善2型糖尿病下肢血管病患者踝肱指数(ABI)和足背动脉峰值流速。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of “Yingwei Fang” on Lower Extremity Vascular Lesions in Patients with Different Syndromic Type 2 Diabetes
Objective: To investigate the changes of ankle-brachial index (ABI) and peak velocity of dorsal foot artery in patients with type 2 diabetes mellitus with lower extremity vascular disease treated with Yingweifang. Methods: 36 cases of type 2 diabetes mellitus with lower extremity vascular disease were observed, including 13 cases of Yin deficiency and hot, 9 cases of qi and Yin deficiency and 14 cases of Yin and Yang deficiency. Oral “Yingwei Fang” capsule, 5 capsules per time, 3 times a day, combined with the dialectical TCM dialectical theory of treatment, conventional treatment such as hypoglycemia. Changes in the ankle-brachial index (ABI) and peak flow rate of dorsal foot artery were measured after 150 days of treatment compared with before treatment. RESULTS: After treatment, ABI and peak flow rate of dorsal foot artery in diabetic lower extremity vascular disease patients were changed in different degrees (P < 0.05, P<0.01), and ABI was improved more obviously (P <0.01). Qi and Yin deficiency and Yin and Yang deficiency were also improved (P<0.05). The comparison of desiccation and heat between Qi and Yin deficiency and Yin deficiency after treatment (P<0.05); CONCLUSIONS: Yingwei Fang can significantly improve the ankle-brachial index (ABI) and peak velocity of dorsal foot artery in patients with lower extremity vascular disease of type 2 diabetes mellitus.
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