A Long-Term Survival Of Small Cell Lung Cancer Developed Diffuse Large B-Cell Lymphoma

We are reporting a rare case of a patient with a long-term survival of a small cell lung cancer (SCLC) who later developed a diffuse large B-cell lymphoma in the left neck. The patient was a smoker, and at age 50, was diagnosed with limited-stage small cell lung cancer. He was treated with chemotherapy and concurrent radiation therapy, and received prophylactic cranial irradiation resulting in a complete remission. Now, eight years later, he has developed an 8 cm mass at the supraclavicular lymph node. Biopsy confirmed a diffuse large B-cell lymphoma. His bone marrow was not involved. With treatment of intense chemotherapy and involved field radiation of the left neck, he is now in complete remission. Long-term survivors of SCLC may develop a second cancer including high-grade lymphoma. Thus, closely following up patients with SCLC is essential.